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| 防风灵——防风中1个新的香豆素类化合物 | |
| 引用本文： | 赵博,杨鑫宝. 防风灵——防风中1个新的香豆素类化合物[J]. 中国中药杂志, 2010, 35(11): 1418-1420 |
| 作者姓名： | 赵博 杨鑫宝 |
| 作者单位： | 1. 吉林农业大学中药材学院,吉林,长春,130118;北京大学药学院天然药物及仿生药物国家重点实验室,北京,100191 2. 北京中医药大学东方学院,河北,廊坊,065001 3. 北京大学药学院天然药物及仿生药物国家重点实验室,北京,100191 4. 吉林农业大学中药材学院,吉林,长春,130118 |
| 基金项目： | 吉林省科技发展基金项目(20060909-07) |
| 摘 要： | 目的:对防风Saposhnikovia divaricata未抽花茎的干燥根的化学成分进行研究。方法:采用硅胶柱色谱方法进行分离、纯化,IR,UV,MS和NMR等方法进行结构鉴定。结果:从防风甲醇提取物的正丁醇萃取物中得到2个化合物,分别鉴定为紫花前胡苷元(1)和8-[4-(β-D-glucopyranosyloxy)-3-methyl-2-buten-1-yl]oxy-5-methoxy-6,7-furanocoumarin(2)。结论:化合物2为新化合物,命名为防风灵(sapodivarin)。 |
| 关 键 词： | 防风 香豆素 防风灵 |
| 收稿时间： | 2010-02-21 |
Sapodivarin, a new coumarin from roots of Saposhnikovia divaricata |
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| ZHAO Bo and YANG Xinbao. Sapodivarin, a new coumarin from roots of Saposhnikovia divaricata[J]. China Journal of Chinese Materia Medica, 2010, 35(11): 1418-1420 | |
| Authors: | ZHAO Bo and YANG Xinbao |
| Affiliation: | College of Traditional Chinese Medicine, Jilin Agricultural University, Changchun 130118, China;State Key Laboratories of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences,Peking University, Beijing 100191, China;Dongfang College, Beijing University of Chinese Medicine, Langfang 065001, China |
| Abstract: | Objective: To study the chemical constituents in the dried roots of Saposhnikovia divaricata (Turcz.) Schischk. Method: The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by IR, UV, MS and NMR evidences. Result: Two compounds were obtained and identified as nodakenetin ( 1 ) and 8- oxy-5-methoxy-6,7-furanocoumarin ( 2 ), respectively. Conclusion: Compound 2 is a new compound and named sapodivarin. |
| Keywords: | Saposhnikovia divaricata coumarin sapodivarin |
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