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INFLUENCE OF ALLOFERIN ON NEUROMUSCULAR FUNCTION IN MYASTHENIA PATIENTS UNDERGOING THYMECTOMY
引用本文:罗霞 叶铁虎 罗爱伦 任洪智 金永芳. INFLUENCE OF ALLOFERIN ON NEUROMUSCULAR FUNCTION IN MYASTHENIA PATIENTS UNDERGOING THYMECTOMY[J]. 中国医学科学杂志(英文版), 1994, 9(1): 56-58
作者姓名:罗霞 叶铁虎 罗爱伦 任洪智 金永芳
作者单位:DepartmentofAnesthesiology,PekingUnionMedicalCollegeHospital,Beijing100730
摘    要:Myasthenia gravis patients are hypersensitive to nondepolarizing relaxants,such as alcuronium,an intermedi-ate-long nondepolarizing agent. This study observed the effects of alcuronium treatment in myasthenia gravis pa-tients as compared with non-MG patients during operation.Ten MG patients (Ossermann class Ⅰ-Ⅳ,scheduled for thymectomy)and 10non-MG patients(ASA class Ⅰ-Ⅱ,scheduled for operation)were selected.An induc-tion dose of alcuronium 0.2 mg/kg and thiopental 4-6 mg/kg was given,followed by intubation and ventilation with 50% nitrous oxide in oxygen and 0.5-1.5% ethrane.Neuromuscular transmission was monitored using an accelerogragh and degrees of neuromuscular function at different depths were recorded.There were statistically significant differences between the tow groups.The effect of alloferin in the MG group was quicker and deeper.This study also found a relation between MG class and the recovery of respiration: Respiratory recovery was quicker in classes Ⅰ-Ⅱ than in classes Ⅲ-Ⅳ.

关 键 词:神经肌肉功能 重症肌无力 胸腺切除术 治疗

INFLUENCE OF ALLOFERIN ON NEUROMUSCULAR FUNCTION IN MYASTHENIA PATIENTS UNDERGOING THYMECTOMY
Luo Xia, Yie Tiehu, Luo Ailun ,Ren Hongzhi, and Jin Yongfang. INFLUENCE OF ALLOFERIN ON NEUROMUSCULAR FUNCTION IN MYASTHENIA PATIENTS UNDERGOING THYMECTOMY[J]. Chinese medical sciences journal, 1994, 9(1): 56-58
Authors:Luo Xia   Yie Tiehu   Luo Ailun   Ren Hongzhi    Jin Yongfang
Abstract:
Keywords:neuromuscular function  myasthenia gravis  alcuronium
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