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Plasmapheresis in the treatment of acute renal failure in multiple myeloma.
Authors:R Misiani  G Remuzzi  T Bertani  R Licini  P Levoni  A Crippa  G Mecca
Institution:Bergamo, Italy
Abstract:Three patients with multiple myeloma and severe acute renal failure were treated by repeated plasmapheresis. Recovery of renal function was observed in all. The pathogenetic role of light chains and the possible mechanisms responsible for renal damage are discussed. It is suggested that the removal of light chains by plasmapheresis may be of therapeutic value in this condition.
Keywords:Requests for reprints should be addressed to Dr  Rocco Misiani  Divisione di Nefrologia e Dialisi  Ospedali Riuniti  Bergamo  Italy  
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