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地龙提取液对哮喘患者血浆中 PGI_2、TXA_2 的影响
引用本文:/Chen Meixi∥Department of Respiratory Diseases,Affiliated Hospital,Guilin Medical College.地龙提取液对哮喘患者血浆中 PGI_2、TXA_2 的影响[J].华夏医学,1997(2).
作者姓名:/Chen  Meixi∥
作者单位:广西桂林医学院附属医院呼吸内科
摘    要:为探讨地龙平喘的作用环节,观察了20例患者用药前后血浆中前列环素、血栓素A2含量及两者比值变化。结果表明:用药后PGI2轻度升高,TXA2降低,但无统计学差异,而PGI2/TXA2比值升高,有统计学差异,提示地龙可通过调节哮喘患者血浆中的PGI2/TXA2比值,发挥平喘作用。

关 键 词:地龙提取液  前列环素  血栓素A_2  哮喘

Influence of Dilong (Earthworm) Extract on Plasma PGI 2 and TXA 2 of Asthmatic Patient
Abstract:In order to explore the possible mechanism of Dilong (earthworm) in treating acute bronchial asthma, the plasma levels of prostacyclin (PGI 2), thromboxane A 2(TXA 2) and the changes of ratio of both in 20 cases before and after treatment were measured. The results showed that PGI 2 level lightly raised and TXA 2 level reduced after drug taking without statistical difference ( P >0.05) but the ratio of PGI 2 and TXA 2 raised with marked difference ( P <0.05), suggesting that Dilong might reach the goal of treating asthma through adjusting the ratio of plasma PGI 2 and TXA 2 of asthmatic patients.
Keywords:Dilong extract  prostacyclin  thromboxane A  2  asthma
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