Graves眼病眼压临床分析

目的 观察和分析Graves眼病(GO)患者眼压的临床特点及影响因素。 方法 分析2012~2013年间内分泌科门诊随访的66例GO患者的临床资料,探讨GO患者眼压升高与年龄、性别、病程、家族史、吸烟史、甲状腺功能、CAS评分及病情严重度评估、眼压情况、治疗情况等的关系。 结果 本组GO患者眼压升高的发生率为45.5%。与正常眼压组比较,高眼压组的患者年龄偏大,突眼程度更重,甲状腺功能异常。但性别、吸烟史、家族史、病程、病情严重度评估及病情活动度评估两组差异无统计学意义。通过积极的治疗,大部分高眼压患者眼压可恢复正常。 结论 GO眼压升高有其独特的临床特点,临床需要关注GO患者的眼压问题。积极有效的GO治疗可使绝大部分患者的眼压控制在正常范围。

Clinical Analysis of Intraocular Pressure in Graves' Ophthalmopathy

Objective To observe and analyze the clinical manifestations and the influencing factors of intraocular pressure in Graves'ophthalmopathy (GO). Methods The clinical data of 66 cases(108eyes)of GO from 2012 to 2013 in outpatient service of Department of Endocrinology & Metabolism were retrospectively analyzed to discuss the relationship between ocular hypertension and age,sex,course of the disease,family history,smoking history,thyroid function,CAS score and severity degree,intraocular pressure situation,treatment and so on. Results It was shown that the incidence of elevated intraocular pressure was 45.5%.Compared with normal intraocular pressure group,the patients of high intraocular pressure group were older,the exophthalmos degree in high intraocular pressure group was heavier,and thyroid function was abnormal.However,gender,smoking history,family history,course of disease,illness severity assessment and CAS score had no significant difference.After treatment,high intraocular pressure in GO patients can be restored to normal. Conclusion High intraocular pressure in GO patients has its clinical characteristics.It needed to focus on the intraocular pressure of GO patients.Through positive and effective treatment,the most of high intraocular pressure in GO patients can be controlled in the normal range.