| 益母草的化学成分 |
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| 引用本文： | 蔡晓菡,车镇涛,吴斌,高慧媛,吴立军.益母草的化学成分[J].沈阳药科大学学报,2006,23(1):13-14,21. |
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| 作者姓名： | 蔡晓菡 车镇涛 吴斌 高慧媛 吴立军 |
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| 作者单位： | 1. 沈阳药科大学,中药学院,辽宁,沈阳,110016
2. 香港中文大学,中医学院,香港,新界,沙田 |
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| 摘 要： | 目的分离、鉴定益母草(Leonurus japonicusHoutt.)提取物中的化学成分。方法采用硅胶柱色谱法、Sephadex LH 20柱色谱法等分离,并通过1H NMR1、3C NMR等谱学技术确定其结构。结果分离得到了5个黄酮类化合物,分别鉴定为5,7,3,′4,′5′五甲氧基黄酮(5,7,3,′4,′5′pen-tamethoxy flavone,Ⅰ)、汉黄芩素(wogonin,Ⅱ)、洋芹素7O葡萄糖苷(apigenin 7Oglucopyra-noside,Ⅲ)、大豆素(daidzein,Ⅳ),槲皮素(quercetin,Ⅴ)。结论其中化合物Ⅰ、Ⅱ、Ⅳ为首次从益母草属中分离得到,Ⅲ、Ⅴ为首次从本种植物中分离得到。
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| 关 键 词： | 益母草 化学成分 黄酮 |
| 文章编号： | 1006-2858（2006）01-0013-02 |
| 收稿时间： | 2005-03-01 |
| 修稿时间： | 2005-03-01 |
Studies on chemical constituents of Leonurus japonicus |
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| CAI Xiao-han,CHE Zhen-tao,WU Bin,GAO Hui-yuan,WU Li-jun.Studies on chemical constituents of Leonurus japonicus[J].Journal of Shenyang Pharmaceutical University,2006,23(1):13-14,21. |
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| Authors: | CAI Xiao-han CHE Zhen-tao WU Bin GAO Hui-yuan WU Li-jun |
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| Institution: | 1. School of Traditional Chinese Materia Medica , Shenyang Pharmaceutical University, Shenyang 110016, China ; 2. School of Chinese Medicine, The Chinese University of Hongkong, Shatin, N T., Hongkong SAR, China. |
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| Abstract: | Objective To isolate and elucidate the structures of the constituents from Leonurus japonicus Houtt.Methods The compounds were isolated by chromatography on silica gel and Sephadex LH-20 column and NMR were employed for structure identification.Results Five compounds were obtained and elucidated as 5,7,3′,4′,5′-pentamethoxy flavone(Ⅰ),wogonin(Ⅱ),apigenin-7-O-glucopyranoside(Ⅲ),daidzein(Ⅳ),quercetin(Ⅴ).Conclusions Compound Ⅰ,Ⅱ and Ⅲ are isolated from Leonurus for the first time,ⅣandⅤ are isolated from Leonurus japonicus Houtt for the first time. |
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| Keywords: | Leonurus japonicus Houtt chemical constituents flavones |
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