135例男性不育症的细胞遗传学分析

目的研究男性染色体异常与男性不育症的关系。方法用常规方法制备外周血淋巴细胞标本,对135例男性不育症患者进行染色体G显带核型分析。结果检出异常核型74例,占全部被检者55％。其中性染色体异常40例。占全部被检者30％,占异常核型54％;常染色体异常34例,占全部被检者25％,占异常核型46％。结论对男性不育症的患者进行染色体检查能对不育夫妇的诊断和治疗提供指导性依据。

Cytogenetics analysis on 135 cases of male infertility

Objective: To study the relations between abnormal chromosome and male infertility. Methods: Chromosome preparations made from peripheral blood lymphocytes by conventional, G banding techniques 135 cases of male infertility. Results: Totally there are 74 cases of chromosome abnonnalities which is 55% in all examiners. They include 40 cases of sex chromosome abnormalities which is 30% in all examiners and 54% in chromosome abnormalities. And there are 34 cases of autosome abnormalities which is 25% in all examiners and 46% in chromosome abnormalities. Conclusion: Chromosome examination to male infertility can aid at the diagnosis and treatment of infer couples.