肺硬化性血管瘤61例的临床病理与外科治疗分析

目的:探讨肺硬化性血管瘤(PSH)的临床病理特点、外科治疗及其预后情况.方法:回顾分析总结我院1970-01/2005-04收治的61例PSH临床病理特点、诊治方法及随访情况.结果:全组男性11例(18.03%),女性50例(81.97%),平均年龄39.24岁;38例(62.30%)无症状.放射影像学表现为边缘清晰的圆形或类圆形软组织结节影,47例(77.05%)密度均匀,14例(22.95%)有钙化;全部行手术治疗,无手术并发症和死亡;术后病理及免疫组化结果证实PSH并支持肿瘤来源于上皮组织;术后平均随访8.25 y,无复发、转移.结论:PSH术前诊断困难,确诊主要依靠术后病理,手术是PSH的有效治疗方法.

Clinicopathological features and surgical treatment of 61 cases with pulmonary sclerosing hemangioma

AIM: To investigate the clinicopathological features, surgical treatment and prognosis of pulmonary sclerosing hemangioma. METHODS: The clinicopathological features, operative treatment and prognosis of 61 patients with pulmonary sclerosing hemangioma in our hospital from January, 1970 to April,2005 were analyzed retrospectively. RESULTS: There were 11 males(18.03%)and 50 females (81.97%). The mean age was 39.24(15-59)years old. The 38(62.30%) patients were free of symptoms . By radiography, the tumor presented as a round or nearly round nodule, with uniform dersity in 47 (77.05%) cases and calcification in 14 (22.95%) cases. All patients received operation, without complications and death. Immunohistochemical findings suggested that the tumor might originate from epithelium. During postoperative follow-up of about 8.25 years, there was no recurrence or metastasis. CONCLUSION: It is very difficult to diagnose pulmonary sclerosing hemoangioma before operation, for it mainly depends on pathological examination postoperatively. A good prognosis can be achieved through surgical treatment.