Corneal argon laser photocoagulation for neovascularization in penetrating keratoplasty |
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| Authors: | V S Nirankari J C Baer |
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| Affiliation: | 1. Intelligent Data Center and Department of Mathematics, Sun Yat-Sen University, Guangzhou 510275, China;2. School of Mathematics, JiaYing University, Meizhou, Guangdong 514015, China;1. Stein Eye Institute, University of California, Los Angeles, Los Angeles, California, USA;2. Devers Eye Institute, Portland, Oregon, USA;3. Case Western Reserve University Department of Ophthalmology and Visual Sciences, University Hospitals Eye Institute, and the Cornea Image Analysis Reading Center, Cleveland, Ohio, USA;4. Jaeb Center for Health Research, Tampa, Florida, USA;5. Center for Preventive Ophthalmology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA;6. Eye Care of San Diego, San Diego, California, USA;7. Michigan Cornea Consultants, P.C., Southfield, Michigan, USA;8. Eye Associates Northwest, Seattle, Washington, USA;9. Wills Eye Hospital, Philadelphia, Pennsylvania, USA;10. Minnesota Eye Consultants, Bloomington, Minnesota, USA;11. University of California, San Francisco, San Francisco, California, USA;12. Northeast Ohio Eye Surgeons, Kent, Ohio, USA;13. Focal Point Vision, San Antonio, Texas, USA;14. Eye Consultants of Maryland, Owings Mills, Maryland, USA;15. Medical Eye Center, Medford, Oregon, USA;p. Ophthalmic Partners of PA, P.C., Bala Cynwyd, Pennsylvania, USA;q. Central Pennsylvania Eye Institute, Hershey, Pennsylvania, USA;r. Eversight, Ann Arbor, Michigan, USA;s. New York Eye and Ear Infirmary, New York, New York, USA;t. Keck Medical Center of University of Southern California, Ophthalmology, Los Angeles, California, USA;u. Lions VisionGift, Portland, Oregon, USA;v. Mercy-St. John''s Clinic, Springfield, Missouri, USA;w. University of Kentucky Department of Ophthalmology, Lexington, Kentucky, USA;x. Verdier Eye Center, Grand Rapids, Michigan, USA;1. Department of Ophthalmology, Amsterdam University Medical Centers, Amsterdam, The Netherlands;2. Department of Hematology, Amsterdam University Medical Centers, Amsterdam, The Netherlands;3. Department of Blood Cell Research, Sanquin Research and Landsteiner Laboratory, Amsterdam, The Netherlands;4. Department of Ophthalmology, University of Lausanne, Jules-Gonin Eye Hospital, Fondation Asile des Aveugles, Lausanne, Switzerland;1. Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10065, USA;2. Modus Outcomes, Spirella Building, Letchworth Garden City, SG6 4ET, UK;3. McMaster University, 3N27, 1200 Main Street W, Hamilton, ON L8N 3Z5, Canada;4. Henry Ford Health System, 2799 W. Grand Blvd, K-16, Detroit, MI 48202, USA |
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| Abstract: | Corneal argon laser photocoagulation (CALP) was used in 13 patients to treat deep stromal vascular ingrowth. Eight patients had undergone successful penetrating keratoplasty but had developed deep stromal vessels into the graft associated with signs of graft rejection, which did not improve with steroid treatment alone (group 1). After CALP, there was marked regression of the neovascularization with reversal of graft rejection in all eyes. Three additional patients with vascularized corneas, referred for penetrating keratoplasty, underwent CALP preoperatively with obliteration of the vessels (group 2). Two of these patients have since undergone keratoplasty and, in both, the grafts have remained avascular and clear over a 21-month follow-up. Two other patients with corneal injury and progressive corneal opacification and vascularization have also been treated with CALP (group 3). CALP may be a useful adjunct in the treatment of corneal neovascularization. Further clinical studies are needed to define its exact role. |
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| Keywords: | corneal argon laser photocoagulation (CALP) graft rejection penetrating keratoplasty progressive corneal opacification stromal neovascularization |
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