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糖尿病视网膜病变患者血清C肽水平的变化
引用本文:焦剑,张仲臣,熊飞,李颖. 糖尿病视网膜病变患者血清C肽水平的变化[J]. 国际眼科杂志, 2008, 8(10): 2040-2043
作者姓名:焦剑  张仲臣  熊飞  李颖
作者单位:北京大学航天中心医院眼科,中国北京市,100049
基金项目:北京大学航天中心医院院级科研基金资助项目(No.200604)~~
摘    要:目的:观察血清C肽与糖尿病视网膜病变的关系。方法:2型糖尿病患者119例根据糖尿病视网膜病变程度分为3组,分别测定其空腹及餐后2h血清C肽的水平,并记录其他可能影响糖尿病视网膜病变发展的因素。结果:增生性糖尿病视网膜病变组空腹及餐后2h血清C肽均最低,背景型糖尿病视网膜病变组次之,logistic回归分析证明餐后2h血清C肽水平是影响糖尿病视网膜病变发展的独立因素。结论:餐后2h血清C肽水平降低是糖尿病视网膜病变发展的危险因素。

关 键 词:C肽  糖尿病  糖尿病视网膜病变

Clinical observation of serum C-peptide concentration and diabetic retinopathy
Jian Jiao,Zhong-Chen Zhang,Fei Xiong,Ying Li. Clinical observation of serum C-peptide concentration and diabetic retinopathy[J]. International Eye Science, 2008, 8(10): 2040-2043
Authors:Jian Jiao  Zhong-Chen Zhang  Fei Xiong  Ying Li
Affiliation:Department of Ophthalmology,the Center Hospital of China Aerospace Corporation,Peking University Health Science Center,Beijing 100049,China
Abstract:AIM:To observe the possible association between serum C-peptide concentration and diabetic retinopathy(DR). METHODS:A total of 119 patients with type 2 diabetic were divided into three groups by the degree of diabetic retinopathy.The concentration of fasting serum C-peptide(FCP)and post-meal 2-hour serum C-peptide(PCP)was examined.At the same time,the possible factors that might affect the DR were recorded. RESULTS:The patients with PDR had the lowest concentration of FCP and PCP 2 hours after meal than oth...
Keywords:C-peptide  diabetes mellitus  diabetic retinopathy  
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