早期干预对新生儿缺氧缺血性脑病智能发育的影响

目的:探讨早期干预对新生儿缺氧缺血性脑病(HIE)智能发育的影响。方法:将60例中、重度HIE患儿随机分为干预组30例和对照组30例。干预组自出生后3～7天即开始采用医院和家庭相结合的方式,接受良好环境刺激和综合康复功能训练,对照组行一般治疗和常规育儿。两组患儿均定期定人于0～1岁时进行智能发育随访。结果:干预组在出生后28天时新生儿行为神经评分(NBNA)和6、9、12个月时发育商(DQ)均高于对照组(P<0.01)。结论:对中、重度HIE患儿进行医院和家庭相结合的早期干预可促进HIE患儿智能发育,降低伤残发生率,促进早期康复,减少后遗症。

Effect of early intervention on the intellectual development of neonatal hypoxic-ischemic encephalopathy

Objective:To investigate the effect of early intervention on the intellectual development of neonatal hypoxic-ischemic encephalopathy(HIE).Methods:60 medium and severe HIE babies were randomly divided into intervention group(30 cases) and control group(30 cases).The intervention group received good environmental stimulation combined with rehabilitation training from 3-7 days of birth in a hospital-family combined way.The control group received general treatment and conventional care.Results:Of the intervention group,NBNA of 28 days of birth and the developmental quotient(DQ) at the age of 6,9,12 months were significantly higher than those of the control group(P<0.01).Conclusion:Hospital-family combined early intervention can promote the intellectual development of medium and severe HIE babies,decrease disability rate,facilitate early rehabilitation and reduce sequel.