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前列腺癌骨转移性疼痛的综合治疗
引用本文:任晓敏,应俊,姚德鸿,叶传扬,蒋跃庆.前列腺癌骨转移性疼痛的综合治疗[J].中华男科学杂志,2004,10(3):188-190.
作者姓名:任晓敏  应俊  姚德鸿  叶传扬  蒋跃庆
作者单位:1. 上海第二医科大学附属第九人民医院泌尿外科,上海,200011
2. 复旦大学附属肿瘤医院核医学科,上海,200032
摘    要:目的 :探讨晚期前列腺癌骨转移性疼痛的综合治疗方法。 方法 :16例确诊为前列腺癌且有多个部位骨转移病灶伴有疼痛的患者 ,采用口服抗雄激素药物治疗的同时 ,辅以核素89Sr静脉内注射治疗和部分病灶放射治疗。 结果 :治疗后 ,疼痛缓解率 3个月为 75 .6 % ,6个月为 80 .5 % ,9个月为 6 3.4 % ;骨转移病灶数量明显减少。结论 :经过综合治疗后 ,本组晚期前列腺癌伴骨转移性疼痛的患者疼痛获得较为满意的缓解、甚至消失 ,从而改善了患者的生活质量。

关 键 词:前列腺癌  骨转移性疼痛  抗雄激素药物  89锶  放射治疗
文章编号:1009-3591(2004)03-0188-03
修稿时间:2003年8月2日

Combined Treatment for Pain from Bone Metastases in Patients with Prostate Cancer
Ren Xiaomin,Ying Jun,Yao Dehong,Ye Chuanyang,Jiang Yueqing.Combined Treatment for Pain from Bone Metastases in Patients with Prostate Cancer[J].National Journal of Andrology,2004,10(3):188-190.
Authors:Ren Xiaomin  Ying Jun  Yao Dehong  Ye Chuanyang  Jiang Yueqing
Institution:Ren Xiaomin,Ying Jun,Yao Dehong,Ye Chuanyang,Jiang Yueqing Department of Urology,Shanghai Ninth People's Hospital Affiliated to Shanghai Second Medical University,Shanghai 200011,China
Abstract:Objective: To evaluate the effects of combined treatment of hormone therapy with strontium 89 for pain from bone metastases in patients with prostate cancer. Methods: Sixteen patients with metastasis prostate cancer received hormone therapy with strontium 89 chloride ( 89 Sr), and 4 of them received radiotherapy. Results: The pain was relieved. Relief occurred in 75.6 % of the patients for 3 months, 80.5 % for 6 months and 63.4 % for 9 months. Conclusion: Hormone therapy enhances the effect of 89 Sr without obvious toxicity. The combined treatment not only significantly raises pain palliation, prolongs pain free survival, but improves the patients' life quality.
Keywords:prostate cancer  pain from bone metastases  hormone therapy  strontium  89  radiation therapy
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