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慢性丙肝相关性脂肪肝与瘦素及胰岛素抵抗的关系研究
引用本文:刘光伟,王春芳,扈晓宇,赵文霞.慢性丙肝相关性脂肪肝与瘦素及胰岛素抵抗的关系研究[J].西部医学,2011,23(12):2326-2327.
作者姓名:刘光伟  王春芳  扈晓宇  赵文霞
作者单位:1. 河南中医学院第一附属医院消化科,河南郑州,200062
2. 成都中医药大学附属医院感染科,四川成都,610072
摘    要:目的观察单纯慢性丙型肝炎与合并脂肪肝的丙肝患者之间病毒载量、瘦素、胰岛素抵抗的差异。方法通过B超筛选慢性丙肝合并脂肪肝患者37例,并与非脂肪变丙肝患者34例比较,观察两组患者病毒载量、肝功能、瘦素、胰岛素抵抗指数差异。结果合并脂肪变的慢性丙型肝炎患者HCV-RNA载量较非脂肪变组明显升高,瘦素水平及胰岛素抵抗较高,HCV-RNA载量与瘦素水平及胰岛素抵抗呈正相关关系,与ALT水平无相关性。结论合并脂肪变的慢性丙型肝炎患者病毒载量与瘦素水平升高及胰岛素抵抗相关。

关 键 词:慢性丙型肝炎  脂肪肝  抗病毒  疗效

Association between leptin and insulin resistance in hepatitis C-related fatty liver
LIU Guang-wei,WANG Chun-fang,HU Xiao-yu,et al.Association between leptin and insulin resistance in hepatitis C-related fatty liver[J].Medical Journal of West China,2011,23(12):2326-2327.
Authors:LIU Guang-wei  WANG Chun-fang  HU Xiao-yu  
Institution:LIU Guang-wei1,WANG Chun-fang1,HU Xiao-yu1,et al (1.The First Affiliated Hospital of Henan College of TCM,Henan College of TCM,Zhengzhou 200062,China,2.The First Affiliated Hospital of Chengdu University of TCM,Chengdu University of TCM,Chengdu 610072,China)
Abstract:Objective To observe the simple merger of chronic hepatitis C and fatty liver of hepatitis C viral load between patients,leptin,insulin resistance.Methods The viral load,liver function,leptin,insulin resistance index of 37 chronic hepatitis C patients with fatty liver(fatty group) and 34 cases without fatty liver(non-fatty group) were analyzed.Results The hepatitis C HCV-RNA load,leptin and insulin resistance of fatty group was higher than that of non-fatty group.HCV-RNA load and leptin levels and insulin r...
Keywords:Chronic hepatitis C  Fatty liver  Anti-virus  Effect  
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