| 兔离体新鲜肝组织的电阻抗温度特性研究 |
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| 引用本文： | 蔡华,尤富生,史学涛,付峰,刘锐岗,汤池,董秀珍.兔离体新鲜肝组织的电阻抗温度特性研究[J].医疗卫生装备,2010,31(11):8-11. |
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| 作者姓名： | 蔡华 尤富生 史学涛 付峰 刘锐岗 汤池 董秀珍 |
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| 作者单位： | 第四军医大学生物医学工程系,西安,710032 |
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| 基金项目： | 军队"十一五"攻关项目 |
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| 摘 要： | 目的：获得肝组织的电导率与温度的关系,为采用电阻抗成像法监测在肝肿瘤热疗时的体内温度奠定基础。方法：采用新鲜离体兔肝,通过模拟肝肿瘤热疗过程,四电极法阻抗盒测量兔肝在受热和冷却的2个阶段的多频电阻抗,研究兔肝组织的电阻抗与温度间的相应关系。结果：在58℃以下、f=1 kHz时,温度-电阻抗变化系数基本上在-1.0%～-2.2%波动。在58～69℃区间,温度-电阻抗变化系数从-2%快速变化至-14.7%。69、70、71℃等3个温度点的温度—电阻抗变化系数均保持在-14.7%附近。在71～76℃区间,温度-电阻抗变化系数从-14.7%快速变化至-1.0%。76℃以上,温度-电阻抗变化系数基本上为-1.0%。结论：兔肝细胞受热变性时电阻抗特性发生显著改变。在临床热疗中,有可能通过监测生物阻抗的改变来监测热疗时的温度。
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| 关 键 词： | 肿瘤热疗 温度 肝组织 电阻抗 |
Electric Impedance Temperature-resistant Characteristics in Fresh Rabbit Liver in Vitro |
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| CAI Hua,YOU Fu-sheng,SHI Xue-tao,FU Feng,LIU Rui-gang,TANG Chi,DONG Xiu-zhen.Electric Impedance Temperature-resistant Characteristics in Fresh Rabbit Liver in Vitro[J].Chinese Medical Equipment Journal,2010,31(11):8-11. |
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| Authors: | CAI Hua YOU Fu-sheng SHI Xue-tao FU Feng LIU Rui-gang TANG Chi DONG Xiu-zhen |
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| Institution: | CAI Hua,YOU Fu-sheng,SHI Xue-tao,FU Feng,LIU Rui-gang,TANG Chi,DONG Xiu-zhen(Department of Biomedical Engineering of the Fourth Military Medical University,Xi'an 710032,China) |
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| Abstract: | Objective To obtain the relationship between conductivity and temperature of liver tissue in order to lay a foundation for monitoring the body temperature during the liver tumor thermotherapy with Electrical Impedance Tomography(EIT).Methods By simulating the course of liver tumor thermotherapy,the multi-frequency electrical impedance of fresh rabbit liver was measured by the four-electrode impedance box in the process of heating and cooling.The corresponding relationship of temperature and electrical imped... |
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| Keywords: | hyperthermia temperature liver tissue impedance |
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