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FENCLOFENAC-INDUCED SELECTIVE IGA DEFICIENCY IN RHEUMATOID ARTHRITIS
Authors:FARR, M.   STRUTHERS, G. R.   SCOTT, D. G. I.   BACON, P. A.
Affiliation:Department of Rheumatology, University of Birmingham, The Medical School Birmingham BIS 2TJ, UK
Abstract:A 35-year-old man with seropositive rheumatoid arthritis developedselective IgA deficiency during treatment with fenclofenac.His arthritis remained quiescent while taking the drug and followingits withdrawal his condition relapsed and his serum IgA levelreturned to normal. This case demonstrates the association ofselective IgA deficiency with remission in rheumatoid arthritisinduced by fenclofenac as well as aurothiomalate and sulphasalazine.It also shows severe relapse after withdrawal of fenclofenac. KEY WORDS: Rheumatoid arthritis, Selective IgA deficiency, Fenclofenac
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