理中化痰丸联合多潘立酮治疗糖尿病胃轻瘫随机平行对照研究

[目的]观察理中化痰丸联合多潘立酮治疗糖尿病胃轻瘫疗效。[方法]使用随机平行对照方法,将76例门诊及住院患者按就诊顺序编号法随机分为两组。对照组38例多潘立酮10mg/次,3次/d,饭后30min口服。治疗组38例理中化痰丸(党参、石菖蒲、生姜、法半夏、茯苓各15g,干姜、炒白术各18g,砂仁12g,炙甘草9g,大枣6g),1剂/d,水煎200mL,饭后2h口服;症状消失后,1剂/d,隔日1次;多潘立酮治疗同对照组。连续治疗30d为1疗程。观测临床症状、FPG、2hPG、HbA1c、复发率、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效17例,有效18例,无效3例,总有效率92.11%。对照组显效11例,有效16例,无效11例,总有效率71.05%。治疗组疗效优于对照组(P0.05)。FPG、2hPG及HbA1c两组均有改善(P0.05),治疗组改善优于对照组(P0.05)。[结论]理中化痰丸联合多潘立酮治疗糖尿病胃轻瘫方面效果显著,值得推广。

Manage the Phlegm Pill Joint Pan Li Ketone Piece more Random Parallel Control Study Treatment of Diabetic Gastroparesis

[ Objective ] To observe the principle of joint much phlegm pill flavored Pan Li ketone curative effect on diabetic gastroparesis. [ Methods ] Using random parallel control method, 76 cases of outpatient and inpatient medical order numbering method were randomly divided into two groups. More than the control group 38 cases Pan Li ketone 10 mg/time, three/d. After 30 min. Continuous treatment of 30 d as a course of treatment. Phlegm pill in the treatment group 38 examples principle flavored （ Dangshen, Shichangpu, Shengjiang, Fabanxia, Fuling each 15g, Ganjiang, Chaobaizhu 18g, Sharen 12g, Zhigancao 9g, Dazao 6g）, water frying 200 mL, l/d, 2 h after the meal. After clinical symptoms disappeared basically, reduced to 1 day, 1 agent/time. Western medicine treatment with the control group. Observation of clinical symptoms, FPG, 2 ttPG, HbA1c, the recurrence rate and adverse reactions. Continuous treatment 1 treatment course, judge curative effect. [ Result ] the treatment group of 17 cases were markedly effective, effective 18 eases, 3 had no effect, the total effective rate was 92.11%. Control group 11 cases were markedly effective, effective in 16 cases, ineffective in 11 cases, total effective rate was 71.05%. The treatment group curative effect is better than that of control group （P〈0.05） . Two groups of FPG, 2 HPG and HbAlc were improved （P〈0.05）, the treatment group is better than that of control group （ P〈0.05 ） . [ Conclusion ] The principle the phlegm pill flavored joint more Pan Li plate in treatment of diabetic gastroparesis effect is remarkable, is worth promoting.