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Mortality due to dapsone hypersensitivity syndrome complicating multi-drug therapy for leprosy in Nepal
Authors:Pandey B  Shrestha K  Lewis J  Hawksworth R A  Walker S L
Affiliation:Department of Medicine, Anandaban Hospital, PO Box 151 Kathmandu, Nepal.
Abstract:Dapsone is a component of multi-drug therapy (MDT) for the treatment of all types of leprosy. It is known that dapsone hypersensitivity syndrome (DHS) complicates the treatment in a proportion of patients. We performed a retrospective study of patients commenced on MDT between 1990 and 2006; 2% developed DHS and 0.25% died due to DHS.
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