Mortality due to dapsone hypersensitivity syndrome complicating multi-drug therapy for leprosy in Nepal |
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Authors: | Pandey B Shrestha K Lewis J Hawksworth R A Walker S L |
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Affiliation: | Department of Medicine, Anandaban Hospital, PO Box 151 Kathmandu, Nepal. |
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Abstract: | Dapsone is a component of multi-drug therapy (MDT) for the treatment of all types of leprosy. It is known that dapsone hypersensitivity syndrome (DHS) complicates the treatment in a proportion of patients. We performed a retrospective study of patients commenced on MDT between 1990 and 2006; 2% developed DHS and 0.25% died due to DHS. |
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