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Association between gene polymorphisms of vitamin D receptor and pulmonary tuberculosis susceptibility:a meta-analysis
Authors:Su Qian    Ma Xiangyu  Lin Hui  Li Ying  Hu Daiyu  Xiong Hongyan  Xu Rufu  Li Yafei
Affiliation:Su Qian1,2,Ma Xiangyu1,Lin Hui1*,Li Ying3,Hu Daiyu2,Xiong Hongyan1,Xu Rufu1,Li Yafei1 1Department of Epidemiology,College of Military Preventive Medicine,Third Military Medical University,Chongqing 400038,China 2Institute of Tuberculosis Prevention and Treatment of Chongqing,Chongqing 400050,China 3Department of Social Medicine and Health Service Management,Chongqing,400038,China
Abstract:Background:The vitamin D receptor(VDR) gene is a primary candidate gene for tuberculosis susceptibility,but results of previous studies are somewhat contradictory and underpowered.Thus,it is essential to further explore the association between VDR gene polymorphisms and risk of pulmonary tuberculosis(PTB).Methods:A systematic review and meta-analysis about the association between FokI,TaqI,ApaI and BsmI polymorphisms and PTB susceptibility was conducted.Statistical Package for Social Science(Version 13.0) a...
Keywords:Vitamin D receptor  Pulmonary tuberculosis  Polymorphism  Meta-analysis  
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