A single nucleotide polymorphism in XRCC4 gene is associated with reduced colorectal cancer susceptibility in female |
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| Authors: | Zhang Zhongheng Hu Weiling Jinhua Central Hospital Jinhua China Sir Run Run Shaw Hospital Hangzhou China |
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| Affiliation: | Zhang Zhongheng1*,Hu Weiling2 1Jinhua Central Hospital,Jinhua 321000,China 2Sir Run Run Shaw Hospital,Hangzhou 310016,China |
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| Abstract: | Objective:To investigate the association of XRCC4 polymorphic variants at G-1394T(rs6869366) with colorectal cancer susceptibility.Methods:In this hospital-based case-control study,the association of XRCC4 polymorphism with colorectal cancer risk in Chinese population was investigated.In total,171 patients with colorectal cancer and 171 healthy individuals matched for age and gender were selected.The genomic DNAs of the patients and controls were extracted from peripheral blood and the 300 bp target DNA was... |
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| Keywords: | XRCC4 Colorectal cancer Single nucleotide polymorphism |
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