| 参一胶囊联合化疗治疗非小细胞肺癌的系统评价 |
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| 引用本文： | 朱际平,于力克,郝可可,张宇,孙子凯.参一胶囊联合化疗治疗非小细胞肺癌的系统评价[J].辽宁中医杂志,2009(9):1444-1447. |
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| 作者姓名： | 朱际平 于力克 郝可可 张宇 孙子凯 |
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| 作者单位： | 南京市胸科医院呼吸一科;江苏省中医院呼吸科; |
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| 摘 要： | 目的:系统评价参一胶囊联合化疗治疗非小细胞肺癌的安全性和有效性。方法:利用计算机和手工方式检索中国期刊全文数据库(CNKI),中文科技期刊全文数据库、PubMed和Cochrane图书馆。检索参一胶囊联合化疗治疗非小细胞肺癌的随机对照临床研究。3位研究者对文献质量进行独立的评价,由Cochrane Collaboration′s software RevMan5.0.1进行Meta分析。结果:共有7项研究被纳入本系统评价,纳入病例535例。Meta分析显示参一胶囊联合化疗治疗非小细胞肺癌与单纯化疗相比,化疗缓解率显著增高(PetoOdds Ratio=2.25,95%CI=1.68~3.76),显著改善患者KPS评分(PetoOdds Ratio=3.57,95%CI=2.19~5.83),延长患者的中位生存期(MD=2.98,95%CI=1.02~4.94)。化疗的毒副反应两组基本相同。结论:参一胶囊联合化疗治疗非小细胞肺癌比单纯化疗有效,不增加化疗的毒副反应。这一证据需要更大规模的多中心随机临床对照研究进一步验证。
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| 关 键 词： | 参一胶囊 非小细胞肺癌 化疗 meta分析 |
Treat Non-small Cell Lung Cancer with Shenyi Capsule plus Chemotherapy:A Systematic Review |
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| ZHU Ji-ping,YU Li-ke,HAO Ke-ke,ZHANG Yu,SUN Zi-kai.Treat Non-small Cell Lung Cancer with Shenyi Capsule plus Chemotherapy:A Systematic Review[J].Liaoning Journal of Traditional Chinese Medicine,2009(9):1444-1447. |
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| Authors: | ZHU Ji-ping YU Li-ke HAO Ke-ke ZHANG Yu SUN Zi-kai |
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| Institution: | 1.Respiratory Department of Nanjing Chest Hospital;Nanjing 210029;Jiangshu;China;2.Respiratory Department of Jiangsu TCM Hospital;China |
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| Abstract: | Objective:To evaluate the efficacy and safety of shenyi capsule plus chemotherapy treated NSCLC.Methods:We searched the CNKI,PubMed,VIP,and Cochrane Library up to the year of 2008.Manual search and additional search were also conducted.Randomized controlled trials of shenyi capsule plus chemotherapy treated NSCLC were included.Three reviewers independently extracted data from eligible studies and evaluated the quality of included studies.Meta-analysis was performed for the results of homogeneous studies by ... |
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| Keywords: | Shenyi Capsule Non-small Cell Lung Cancer Chemotherapy Systematic Review |
| 本文献已被 CNKI 维普 等数据库收录！ |
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