中青年与老年阻塞性睡眠呼吸暂停低通气综合征患者中医证候分布特点及差异

目的:探讨中青年与老年阻塞性睡眠呼吸暂停低通气综合征(OSAHS)患者中医证候分布特点及差异。方法:选取OSAHS患者135例,按照年龄划分标准分为中青年组(18~59岁)67例和老年组(≥60岁)68例,比较2组中医证候分布特点及差异。结果:135例患者的舌脉象进行分析可见,大部分患者表现为舌淡暗、舌苔白腻,脉弦,中青年组患者舌淡暗比例低于老年组,而舌苔白腻患者比例高于老年组。老年组患者以痰瘀互结证为主要证型,患者比例明显高于中青年组(P<0.05);中青年组患者中,脾虚湿瘀证患者比例要明显高于老年组(P<0.05)。结论:OSAHS的发病与肺、脾、肾密切相关。中医证候方面,老年患者多以痰瘀互结证和气虚痰瘀证为主,中青年人群则以痰瘀互结证和脾虚湿瘀证为主,故而临床治疗时应根据患者实际情况对证治疗。

Characteristics and Differences in Chinese Medicine Syndrome Distribution of Obstructive Sleep Apnea Hypopnea Syndrome in Middle-young and Elderly Patients

Objective:To discuss the characteristics and differences in Chinese medicine syndrome distribution of obstructive sleep apnea hypopnea syndrome(OSAHS)in middle-young and elderly patients.Methods:Selected 135 cases of patients with OSAHS,and divided them into the middle-young group(18 to 59 years old)and the elderly group(no less than60 years old),67 cases in the middle-young group and 68 cases in the elderly group.Compared the characteristics and differences in Chinese medicine syndrome distribution in two groups.Results:A visible analysis was conducted for the tongue pulse of patients in both groups.Most patients showed a pale-dingy tongue,white-greasy tongue coating and a wiry pulse.The proportion of patients with a pale-dingy tongue in the middle-young group was lower than that in the elderly group,while the proportion of patients with white-greasy tongue coating were higher than that in the elderly group.Turbidphlegm and blood-stasis syndrome was the main syndrome for patients in the elderly group,and the proportion of patients was obviously higher than that in the middle-young group(P<0.05);among patients of the middle-young group,the proportion of patients with spleen-deficiency and dampness-stasis syndrome was evidently higher than that in the elderly group(P<0.05).Conclusion:The onset of OSAHS was relevant to liver,spleen and kidney.Regarding Chinese medicine syndromes,the turbid-phlegm and blood-stasis syndrome and qi-deficiency and turbid-phlegm syndrome were the main syndrome types for elderly patients,while the turbid-phlegm and blood-stasis syndrome and spleen-deficiency and dampness-stasis syndrome were the main syndrome types for the middle-young group.Therefore,the clinical treatment should be made on the basis of syndrome differentiation and the actual situation of patients.