| “三仙”的不同炮制品对大鼠胃液、胃酸、胃蛋白酶分泌的影响 |
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| 引用本文： | 王颖,李毅,陈勇,杨敏,张钟俐,舒波,张廷模.“三仙”的不同炮制品对大鼠胃液、胃酸、胃蛋白酶分泌的影响[J].四川中医,2011(12):41-43. |
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| 作者姓名： | 王颖 李毅 陈勇 杨敏 张钟俐 舒波 张廷模 |
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| 作者单位： | [1]成都中医药大学,四川成都610075 [2]川北医学院附属医院,四川南充637000 |
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| 基金项目： | 四川省中医药管理局课题（2008-13） |
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| 摘 要： | 目的：观察＂三仙＂不同炮制品对实验大鼠胃酸、胃液、胃蛋白酶分泌的影响。方法：实验大鼠末次灌胃后采用大鼠幽门结扎法造模,3h后观察各组大鼠胃液、胃酸、胃蛋白酶分泌的变化。结果：和空白组相比,养胃舒颗粒组的胃液量增加（P〈0.05）,生品的中剂量组胃液分泌量增加（P〈0.05）;养胃舒颗粒组的胃酸（PH）降低（P〈0.05）,生品的中剂量组胃酸（PH）明显降低（P〈0.05）;养胃舒颗粒的胃蛋白酶活性升高（P〈0.05）,生品的中剂量组胃蛋白酶活性显著升高（P〈0.01）,生品的低剂量组胃蛋白酶活性升高（P〈0.05）。结论：三仙的生品具有促进大鼠胃酸分泌、增加胃液分泌量、促进胃蛋白酶活性的作用。
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| 关 键 词： | “三仙” 炮制 胃酸 胃液 胃蛋白酶 |
The Effects of Pre-processing,Stir-flying and Stir-bake to Brown of Sanxian on Gastric Juice,Gastric Acid and Pepsin of Rats |
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| Wang Ying Li Yi Chen Yong Yang Min Shu Bo Zhang Tingmo.The Effects of Pre-processing,Stir-flying and Stir-bake to Brown of Sanxian on Gastric Juice,Gastric Acid and Pepsin of Rats[J].Journal of Sichuan of Traditional Medicine,2011(12):41-43. |
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| Authors: | Wang Ying Li Yi Chen Yong Yang Min Shu Bo Zhang Tingmo |
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| Institution: | Wang Ying Li Yi Chen Yong Yang Min Shu Bo Zhang Tingmo .Chengdu University of Traditional Chinese Medicine(Chengdu Sichuan 610075,China)2.The Affiliated Hospital of North Sichuan Medical College(Nanchong Sichuan 63700,China) |
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| Abstract: | Objective：To observe the effects of Pre-processing Sanxian,stir-flying and stir-bake to brown of Sanxian on gastric juice,gastric acid and pepsin of rats.Methods： Model rats were induced by ligating pylorus after three hours,then observed the change of gastric juice,gastric acid and pepsin.Results： Compared with normal group,the gastric juice quantity of Yangweishu granule group was increased（P0.05）;the gastric juice quantity of middle dose group was increased in the pre-processing Sanxian（P0.05）;the gastric acid（PH） of Yangweishu granule group was decreased（P0.05）;the gastric acid（PH）of middle dose group was decreased in the pre-processing Sanxian（P0.05）;the pepsin of YangWeiShu granules group was increased（P0.05）;the pepsin of middle dose group was obviously increased in the pre-processing Sanxian（P0.01）;the pepsin of low dose group was increased in the pre-processing Sanxian（P0.05）.Conclusion： The pre-processing Sanxian can promote the secretion of gastric juice,gastric acid and pepsin of rats. |
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| Keywords: | Sanxian processing Gastric juice Gastric Acid Pepsin |
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