藻酸钙纤维联合普米克令舒在鼻内镜术后填塞效果的临床观察

目的探讨Sorbaglon藻酸钙纤维及普米克令舒在鼻内镜术后填塞的临床疗效。方法随机选取80例慢性鼻窦炎的患者,其中Ⅱ型1期27例,Ⅱ型2期34例,Ⅱ型3期19例,采用双侧鼻腔自身对照,随机选取一侧鼻腔作为藻酸钙纤维填塞组（对照组）,另一侧鼻腔作为藻酸钙纤维和普米克令舒填塞组（治疗组）,观察术后患者术腔粘膜的转归过程。结果普米克令舒治疗组,术后鼻腔粘膜肿胀反应轻,肉芽、瘢痕粘连发生率低于对照组,两组术腔上皮化的平均时间经t检验,P〈0.05,可以认为上皮化的时间差异有统计学意义。从疗效分析,治疗组治愈48例,好转23例,治疗有效率88.75%;对照组治愈45例,好转22例,治疗有效率83.75%,经2χ检验,P〉0.05,不能认为两组疗效不同。结论慢性鼻窦炎术后使用藻酸钙纤维联合普米克令舒填塞鼻腔能进一步减轻术腔的术后反应,促进粘膜上皮化进程和粘膜的顺利转归。

Effect of sorbaglon combined with pulmicort respule on rehabilitation after functional endoscopic sinus surgery

Objective To investigate the effect of sorbaglon combined with pulmicort respule on rehabilitation of patients subjected to functional endoscopic sinus surgery.Methods 80 patients suffering from chronic rhinosinusitis were enrolled in the test,in which there were 27 cases of polyposis type Ⅱ stage 1,34 cases of type Ⅱstage 2 and 19 of typeⅡ stage 3.In this self-controlled study,one of the nostrils was randomly choosed as the test group,packed with sorbaglon combined with pulmicort respule.Another nostril was control group,packed sorbaglon only.Results The excretions were decreased,the mucosa intumescence was diminished,and epithelization was established in a shorter time in the test group than in the control group.The difference of the average time to get epithelization between the two groups was proved（P0.05）.And the effective rate was 88.75%in the experimental group and 83.75%in the control group（P0.05）.There were no significant differences between the two groups.Conclusion Using sorbaglon combined with pulmicort respule locally is a benefit for relieving mucosa inflammation,shortening the stage of epithelization,and accelerating the recovery of mucosa after FESS.