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卵巢癌患者血清CA125、TNF、IL-8水平变化及其临床意义
引用本文:时步卿,刘忠娟.卵巢癌患者血清CA125、TNF、IL-8水平变化及其临床意义[J].放射免疫学杂志,2005,18(4):274-275.
作者姓名:时步卿  刘忠娟
作者单位:江苏省赣榆县人民医院,222100;江苏省赣榆县人民医院,222100
摘    要:目的:探讨了卵巢癌患者血清中CA125、TNF、IL-8水平的变化及临床意义。方法:应用放射免疫分析检测了32例卵巢癌患者血清中CA125、TNF、IL-8水平,并与30名正常健康人作比较。结果:卵巢癌患者血清中CA125、TNF、IL-8水平非常显著地高于正常人组(P<0.01)。结论:测定卵巢癌患者血清中CA125、TNF、IL-8水平的变化对患者的治疗和预后均有十分重要的临床价值。

关 键 词:卵巢癌  糖类抗原-125  肿瘤坏死因子  白细胞介素-8
收稿时间:2005-03-06
修稿时间:2005年3月6日

Clinical Significance of Changes of Serum CA125, TNF and IL-8 Levels in Patients with Ovarian Cancer
Shi Buqing,Liu Zhongjuan.Clinical Significance of Changes of Serum CA125, TNF and IL-8 Levels in Patients with Ovarian Cancer[J].Journal of Radioimmanology,2005,18(4):274-275.
Authors:Shi Buqing  Liu Zhongjuan
Abstract:Objective To study the clinical significance of determination of serum CA125, TNF and IL-8 levels patients with ovarian cancer. Methods Serum concentrations of CA125, TNF and IL-8 were measured with RIA in 32 patients with ovarian cancer and 30 controls. Results The serum levels of CA125, TNF and IL-8 were significantly higher in the patients with ovarian cancer than those in the controls (P<0.01). Conclusion Detection of serum CA125, TNF and IL-8 levels in patients with ovarian cancer might be of value for assessing the threapeutic effect and prognosis.
Keywords:ovarian cancer  carbohydrate antigen 125(CA125)  tumor necrosis factor(TNF)  interlukin-8(IL-8)
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