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| 苍白球损毁术中微电极的位置识别方法 | |
| 引用本文： | 刘新文,王惠南,钱志余,杨天明,顾月清.苍白球损毁术中微电极的位置识别方法[J].生物医学工程学杂志,2007,24(3):488-491. |
| 作者姓名： | 刘新文 王惠南 钱志余 杨天明 顾月清 |
| 作者单位： | 1. 南京航空航天大学,自动化学院,生物医学工程系,南京,210016 2. 东南大学,附属中大医院,神经外科,南京,210009 3. 中国药科大学,生命科学与技术学院,南京,210009 |
| 摘 要： | 在治疗帕金森病的苍白球损毁外科手术中,微电极在苍白球中的位置只能通过分析微电极测量的细胞放电特征,依靠主观经验判定。我们以临床微电极信号为基础,利用峰峰时间间隔因子,提出了客观定量的识别微电极位置的方法。该方法能有效的识别出沿微电极针道苍白球组织的变化以及针道是否偏离,识别结果与苍白球解剖结构和手术情况相吻合,此方法可用于临床手术导向。 |
| 关 键 词： | 帕金森病 苍白球 微电极 卡方检验 |
| 修稿时间： | 2005-01-182005-05-12 |
Method of Localization of Microelectrode in the Globus Pallidus during Pallidotomy for Parkinson's Disease |
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| Liu Xinwen,Wang Huinan,Qian Zhiyu,Yang Tianming,Gu Yueqing.Method of Localization of Microelectrode in the Globus Pallidus during Pallidotomy for Parkinson''''s Disease[J].Journal of Biomedical Engineering,2007,24(3):488-491. | |
| Authors: | Liu Xinwen Wang Huinan Qian Zhiyu Yang Tianming Gu Yueqing |
| Institution: | Department of Biomedical Engineering, College of Automation Engineering, Nanjing University of Aeronautics and Astronautics, Nanjing 210016, China. lxwlq2003@163.com |
| Abstract: | Intraoperative analysis of the position of microelectrode in the globus pallidus only depends on experiences and subjective interpretation of microeletrode recording discharge of neurons during pallidotomy for Parkinson's disease.In this paper is reported a method for objective localization of microeletrode during neurosurgery.This method uses the factor of interspike interval based on microelectrode recordings.It is effective for identifying the change of the globus pallidal organism along the microelectrode pathway and the departure or deviation of the needle-pathway.The classification is consistent with the anatomic structures and the results of neurosurgery.This method can be used as a guide in pallidotomy. |
| Keywords: | Parkinson's disease(PD)Globus pallidus Microelectrode Chi-square test |
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