| 氦氖激光治疗剂量的细胞遗传学效应 |
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| 引用本文： | 丁爱华,顾祖维,孙时芬,张伟,许兴娣,黄雷鸣,于继慧. 氦氖激光治疗剂量的细胞遗传学效应[J]. 复旦学报(医学版), 1985, 0(5) |
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| 作者姓名： | 丁爱华 顾祖维 孙时芬 张伟 许兴娣 黄雷鸣 于继慧 |
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| 作者单位： | 上海第一医学院妇产科医院(丁爱华，孙时芬，许兴娣)，上海第一医学院细胞毒理室(顾祖维，张伟，黄雷鸣)，上海第一医学院细胞毒理室(于继慧) |
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| 摘 要： | 用小鼠骨髓多染红细胞和人外周血淋巴细胞的微核试验,评价了氦氖激光常用治疗剂量下的细胞遗传效应。雌性小鼠单独受激光照射或先腹腔注射10 mg/kg血卟啉衍生物(简称HPD)后再照射。激光受试的最大剂量为80 mW。结果表明,即使在最大剂量组并给予血卟啉衍生物,受试组与对照组的微核率无明显差别。
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| 关 键 词： | 血卟啉衍生物 氦氖激光 微核 细胞遗传学 |
OBSERVATIONS ON THE CYTOGENETIC EFFECTS OF THERAPEUTIC DOSES OF HELIUM-NEON LASER BY THE MICRONUCLEUS TEST |
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| DING AIHUA,Gu ZUWEI,SHUN SHIFENG,ZHANG WEIM,Xu XINGET,HUANG LEIMING,Yu JIHUEI. OBSERVATIONS ON THE CYTOGENETIC EFFECTS OF THERAPEUTIC DOSES OF HELIUM-NEON LASER BY THE MICRONUCLEUS TEST[J]. Fudan University Journal of Medical Sciences, 1985, 0(5) |
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| Authors: | DING AIHUA Gu ZUWEI SHUN SHIFENG ZHANG WEIM Xu XINGET HUANG LEIMING Yu JIHUEI |
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| Abstract: | The micronucleus test using mouse polychromatic bone marrow erythrocytes and human peripheral blood lymphocytes was carried out to evaluate the cytogenetio effect of the He-Ne laser therapy used in gynecology. Female mice with and without ip injection of a hematoporphyrin derivative 10mg/kg were irradiated. The maximal dose of laser was 80mW. There was no apparent difference in the frequency of the appearance of micronuclei between treated and untreated mice.Micronuolei of blood lymphocytes in women patients treated were examined before, during and after treatment by laser. No difference in the micronuoleus test was observed. |
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| Keywords: | hematoporphyrin derivative helium-neon laser micronucleus cytogenetics |
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