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石榴不同药用部位对中枢神经系统疾病的作用机制研究进展
引用本文:赵丽蓉,田弥,黎晨,邓针华,黄正元,周本宏.石榴不同药用部位对中枢神经系统疾病的作用机制研究进展[J].中国现代中药,2023,25(6):1366-1375.
作者姓名:赵丽蓉  田弥  黎晨  邓针华  黄正元  周本宏
作者单位:1.武汉大学 人民医院 药学部,湖北 武汉 430060;2.武汉大学 药学院,湖北 武汉 430072
基金项目:国家自然科学基金项目(31770381)
摘    要:中药对中枢神经系统(CNS)疾病的作用和机制是近年来研究的热点。石榴科植物石榴Punica granatum L.对CNS疾病的作用受到广泛关注,石榴籽、石榴皮、石榴花、石榴汁等不同药用部位均被发现可用于治疗CNS疾病。因此,对石榴不同药用部位成分进行比较,并总结各个药用部位对不同CNS疾病(阿尔茨海默病、帕金森病、神经胶质瘤、创伤性脑损伤等)的作用,为进一步研究石榴治疗CNS疾病的物质基础及作用机制、发挥其药用价值提供参考。

关 键 词:石榴皮  石榴籽  石榴汁  石榴花  中枢神经系统
收稿时间:2023/2/24 0:00:00

Research Progress on Mechanism of Different Medicinal Parts of Punica granatum on Central Nervous System Diseases
ZHAO Li-rong,TIAN Mi,LI Chen,DENG Zhen-hu,HUANG Zheng-yuan,ZHOU Ben-hong.Research Progress on Mechanism of Different Medicinal Parts of Punica granatum on Central Nervous System Diseases[J].Modern Chinese Medicine,2023,25(6):1366-1375.
Authors:ZHAO Li-rong  TIAN Mi  LI Chen  DENG Zhen-hu  HUANG Zheng-yuan  ZHOU Ben-hong
Institution:1.Department of Pharmacy, Renmin Hospital of Wuhan University, Wuhan 430060, China;2.School of Pharmaceutical Sciences, Wuhan University, Wuhan 430072, China
Abstract:The role and mechanism of Chinese medicine in central nervous system (CNS) diseases have been a hot topic in recent years. The effects of Punica granatum L., a Punicaceae plant, on CNS diseases have received widespread attention. Different medicinal parts of the P. granatum, such as seeds, peel, flowers, and juice, have been found to be effective in treating CNS diseases. Therefore, this study compared the components of different medicinal parts of P. granatum and summarized their effects on various CNS diseases (such as Alzheimer''s disease, Parkinson''s disease, glioma, and traumatic brain injury), aiming to provide a reference for further investigating the material basis and mechanism of action of P. granatum in the treatment of CNS diseases and exerting its medicinal value.
Keywords:Punica granatum peel  P  granatum seed  P  granatum juice  P  granatum flower  central nervous system
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