Evaluation of MAST-26, newly developed system for the detection of IgE antibodies] |
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| Authors: | T Nakagawa Y Komase Z Ikezawa M Aihara E Iwasaki K Okubo M Hasegawa K Akiyama T Miyamoto |
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| Institution: | Dept. of Internal Medicine, St. Marianna University School of Medicine. |
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| Abstract: | MAST-26 is a new allergy testing system which allows simultaneous determination of allergen-specific IgE antibody levels for 26 allergens using 200 microliters of patient serum. To evaluate the effectiveness of MAST-26 for the detection of allergen-specific IgE antibody, a total of 100 serum samples were collected from allergic patients at five facilities, and allergen-specific IgE antibody was measured by MAST-26. 14% of them were positive to > or = 10 allergens. If the patients had severe allergic symptoms, they were likely to show positive to many allergens. A good correlation was found between the results obtained by MAST-26 with those measured by CAP RAST and by intradermal skin test. It was concluded that MAST-26 is an effective screening method for the detection of allergen-specific IgE. |
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