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A phase 1 study of the antibody-drug conjugate brentuximab vedotin with re-induction chemotherapy in patients with CD30-expressing relapsed/refractory acute myeloid leukemia
Authors:Rupa Narayan MD  Traci M Blonquist MS  Ashkan Emadi MD  PhD  Robert P Hasserjian MD  Meghan Burke BS  Christopher Lescinskas BS  Donna S Neuberg ScD  Andrew M Brunner MD  Gabriela Hobbs MD  Hanno Hock MD  PhD  Steven L McAfee MD  Yi-Bin Chen MD  Eyal Attar MD  Timothy A Graubert MD  Christina Bertoli MSN  Jenna A Moran MSN  Meghan K Bergeron MSN  Julia E Foster MSN  Aura Y Ramos BSN  Tina T Som BSN  Megan K Vartanian BSN  RN  Jennifer L Story LPN  Kristin McGregor MS  Molly Macrae BS  Tanya Behnan BS  Margaret C Wey PhD  Jessica Rae BSN  Frederic I Preffer PhD  Patricia Lesho BA  Vu H Duong MD  Mason L Mann BA  Karen K Ballen MD  Christine Connolly BS  Philip C Amrein MD  Amir T Fathi MD
Institution:1. Division of Hematology/Oncology, Massachusetts General Hospital, Boston, Massachusetts;2. Division of Biostatistics, Dana-Farber Cancer Institute, Boston, Massachusetts;3. Division of Hematology/Oncology, University of Maryland Marlene and Stewart Greenebaum Comprehensive Cancer Center, Baltimore, Maryland
Abstract:
Keywords:acute myeloid leukemia  antibody-drug conjugate  brentuximab vedotin  CD30  cytarabine  etoposide  immunoconjugate  Ki-1 antigen  mitoxantrone  refractory  relapsed
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