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Phase 2 study of afatinib among patients with recurrent and/or metastatic esophageal squamous cell carcinoma
Authors:Min Hee Hong MD  Seong Gu Heo PhD  Yun-Gyoo Lee MD  PhD  Hyo Song Kim MD  PhD  Keon Uk Park MD  PhD  Hoon-Gu Kim MD  PhD  Yoon Ho Ko MD  PhD  Ik-Joo Chung MD  PhD  Young Joo Min MD  PhD  Min Kyoung Kim MD  PhD  Kyu Ryung Kim PhD  Jinseon Yoo MS  Tae-Min Kim MD  PhD  Hye Ryun Kim MD  PhD  Byoung Chul Cho MD  PhD
Affiliation:1. Division of Medical Oncology, Department of Internal Medicine, Yonsei Cancer Center, Yonsei University College of Medicine, Seoul, Korea;2. JE-UK Institute for Cancer Research, JEUK Company Ltd, Gumi-City, Kyungbuk, Korea;3. Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea;4. Division of Hematology/Oncology, Department of Internal Medicine, Keimyung University Dongsan Medical Center, Daegu, Korea;5. Department of Internal Medicine, Institute of Health Sciences, Gyeongsang National University Hospital, Gyeongsang National University School of Medicine, Jinju, Korea;6. Division of Oncology, Department of Internal Medicine, Uijeongbu St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea;7. Department of Hemato-Oncology, Chonnam National University Hwasun Hospital, Hwasun, Korea;8. Department of Hematology and Oncology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Korea;9. Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea;10. Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Korea

Cancer Research Institute, College of Medicine, The Catholic University of Korea, Seoul, Korea;11. Department of Medical Informatics, College of Medicine, The Catholic University of Korea, Seoul, Korea

Abstract:
Keywords:afatinib  epidermal growth factor receptor (EGFR) mutation  esophageal squamous cell carcinoma (ESCC)  predictive biomarker  TP53 mutation
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