Spectrum of PALB2 germline mutations and characteristics of PALB2-related breast cancer: Screening of 16,501 unselected patients with breast cancer and 5890 controls by next-generation sequencing期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Spectrum of PALB2 germline mutations and characteristics of PALB2-related breast cancer: Screening of 16,501 unselected patients with breast cancer and 5890 controls by next-generation sequencing

Authors:	Jiaojiao Zhou MD PhD Honglian Wang PhD Fangmeng Fu MD Zhanwen Li MD Qingjian Feng MD Weizhu Wu MD Yun Liu PhD Chuan Wang MD PhD Yiding Chen MD PhD

Affiliation:	1. Department of Breast Surgery, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China;2. AITA Biomedical Research Institute, Shanghai, China;3. Department of Breast Surgery, Affiliated Union Hospital, Fujian Medical University, Fuzhou, China;4. Department of Breast Surgery, Women and Children's Hospital of Ningbo, Ningbo, China;5. Department of Breast Surgery, Yiwu Maternity and Child Care Hospital, Yiwu, China;6. Department of Thyroid and Breast Surgery, Ningbo Medical Center, Li Huili Eastern Hospital, Ningbo, China;7. Key Laboratory of Molecular Medicine, Ministry of Education, Department of Biochemistry and Molecular Biology, Shanghai Medical College, Fudan University, Shanghai, China

Abstract:

Keywords:	breast cancer risk clinical characteristics germline mutation next-generation sequencing partner and localizer BRCA2 (PALB2)