| 老年慢性阻塞性肺疾病患者血浆肥胖抑制素浓度与CAT评分及6分钟步行距离的相关性研究 |
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| 引用本文： | 赵云峰,孙荣,鲁晓怡,胡慧芳.老年慢性阻塞性肺疾病患者血浆肥胖抑制素浓度与CAT评分及6分钟步行距离的相关性研究[J].老年医学与保健,2019,25(1):86-88,92. |
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| 作者姓名： | 赵云峰 孙荣 鲁晓怡 胡慧芳 |
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| 作者单位： | 上海市浦东新区浦南医院呼吸内科,上海,200125;日本岛根大学医学部,日本岛根693-8501;上海杨思医院呼吸内科,上海,200126 |
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| 基金项目： | 上海市卫生计生委科研项目;上海市浦东新区卫生系统重点专科培养计划;上海市浦东新区卫生系统领先人才培养计划 |
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| 摘 要： | 目的探讨不同体重C级、D级老年慢性阻塞性肺疾病(COPD)患者的血浆肥胖抑制素(obestatin)浓度与CAT评分、6分钟步行距离的相关性。方法选取COPD急性加重患者120例,根据BMI指数分为3组:A组为低体重组(BMI<18.5 kg/m2,40例)、B组为正常体重组BMI在(18.5～24.9)kg/m2范围,40例]和C组为超体重组(BMI>24.9kg/m2,40例)。3组患者分别于入院时、出院时、出院后6个月和12个月测定血浆Obestatin浓度、记录CAT评分及6分钟步行距离。结果 3组患者在不同时间点血浆Obestatin浓度与CAT评分均呈正相关(P均<0.05),与6分钟步行距离均呈负相关(P均<0.05),并且CAT评分与6分钟步行距离均呈负相关(P均<0.05)。结论血浆Obestatin浓度与老年COPD患者CAT评分呈正相关性,与6分钟步行距离呈负相关性。
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| 关 键 词： | 老年 慢性阻塞性肺疾病 肥胖抑制素 慢性阻塞性肺疾病评估试验 6分钟步行距离 |
Study on the Correlation among Plasma Obestatin concentration and CAT Score and 6-minute Walking Distance in Elderly Patients with Chronic Obstructive Pulmonary Disease |
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| Zhao Yunfeng,Sun Rong,Lu Xiaoyi,Hu Huifang.Study on the Correlation among Plasma Obestatin concentration and CAT Score and 6-minute Walking Distance in Elderly Patients with Chronic Obstructive Pulmonary Disease[J].Geriatrics & Health Care,2019,25(1):86-88,92. |
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| Authors: | Zhao Yunfeng Sun Rong Lu Xiaoyi Hu Huifang |
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| Institution: | (Department of Respiratory Disease,Punan Hospital,Pudong New Area,Shanghai,200125,P.R.China;Department of Internal Medicine,Division of Clinical Oncology and Respiratory Medicine,Shimane University Faculty of Medicine,Shimane,693-8501,Japan;Department of Respiratory Disease,Yangsi Hospital,Shanghai,200126,P.R.China) |
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| Abstract: | Zhao Yunfeng;Sun Rong;Lu Xiaoyi;Hu Huifang(Department of Respiratory Disease,Punan Hospital,Pudong New Area,Shanghai,200125,P.R.China;Department of Internal Medicine,Division of Clinical Oncology and Respiratory Medicine,Shimane University Faculty of Medicine,Shimane,693-8501,Japan;Department of Respiratory Disease,Yangsi Hospital,Shanghai,200126,P.R.China) |
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| Keywords: | elderly chronic obstructive pulmonary disease(COPD) obestatin chronic obstructive pulmonary disease assessment test(CAT) 6-minute walking distance(6MWD) |
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