IgM binding to sialosyllactosaminylparagloboside in a patient with polyradiculoneuropathy due to Mycoplasma pneumoniae infection |
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| Authors: | T. Inuzuka N. Miyatani H. Baba M. Tanaka K. Tanaka S. Sato K. Nakamura T. Miyatake |
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| Affiliation: | Department of Neurology, Niigata University, Japan. |
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| Abstract: | IgM in serum without paraprotein in a patient with polyradiculoneuropathy due to a Mycoplasma pneumoniae infection reacted specifically with a ganglioside, sialosyllactosaminylparagroboside (SLPG), in a human peripheral nerve on a thin-layer chromatogram plate by an immunostaining technique. This finding suggests the possibility that anti-SLPG antibody in the patient's serum may play a role in the pathogenesis of neuropathy. |
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| Keywords: | Mycoplasma pneumoniae polyradiculoneuropathy ganglioside cold hemaglutinin |
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