老年难治性原发性高血压患者动态血压与靶器官损害临床分析

目的探讨老年难治性原发性高血压患者动态血压与靶器官损害的关系。方法94例老年难治性原发性高血压患者,经动态血压监测分为持续性高血压组(51例)和白大衣效应高血压组(43例),均进行相关的临床、实验室及超声心动图检查,对有关数据进行t检验或χ2检验进行比较。结果持续性高血压组的平均血压、脉压、非勺型动态血压节律、高血压肾病、左心室肥厚等方面均较白大衣效应高血压组明显升高(P<0.05)。结论持续性高血压患者比白大衣效应高血压患者有更多的靶器官损害,需进一步治疗。

Analysis of ambulatory blood pressure and target organ damage in aged patients with refractory essential hypertension

Objective To detect the correlation of ambulatory blood pressure (ABP) and target organ damage in aged patients with refractory essential hypertension.Methods 94 aged patients with refractory essential hypertension were divided into sustained hypertension group and white-coat effect hypertension group after ambulatory blood pressare monitoring.All were submitted to clinical,laboratory and echocardiographic evaluation.The T-test and chi-squared test was used for comparison among categorical variables.Results The sustained hypertension group had a higher average blood pressure,a larger pulse pressure and a more frequency of non-dippers,and higher rate of hypertension nephropathy and left ventricular hypertrophy than white-coat effect hypertension group~(P<0.05) .Conclusion Sustained hypertension group has more target organ damaged than white-coat effect hypertension group.Further treatment is required.