Primary lymphoblastic B-cell lymphoma of the cranial dura mater: a case report and review of the literature |
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Authors: | Abdullah Sakher Morgensztern Daniel Rosado Manuel F Lossos Izidore S |
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Institution: |
a Department of Medicine, Division of Hematology/Oncology,
b Department of Molecular and Cellular Pharmacology, University of Miami/Sylvester Cancer Center, Miami, FL, USA |
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Abstract: | Primary lymphomas of the cranial dura mater are rare. Mucosa-associated lymphoid tissue extranodal marginal zone lymphomas are the most common subtype of non-Hodgkin's lymphomas that present as primary cranial dura tumors. A 33 year-old male presented with a 3-month history of a growing lump in the right frontal area. Neuroimaging studies demonstrated an extra-axial, broad-based mass with a dural tail in the right frontal bone convexity. Biopsy led to the diagnosis of localized dural precursor B-cell lymphoblastic lymphoma. The patient was treated with a combination of chemotherapy and radiotherapy, achieving durable disease-free survival. This is the first report of precursor B-cell lymphoblastic lymphoma of dura mater. A review of the literature on primary lymphomas of cranial dura mater is presented. |
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Keywords: | Cranial dura lymphoma lymphoplastic lymphoma marginal zone lymphoma |
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