| 酒石酸锗复合物的镇痛作用 |
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| 引用本文： | 金正男,徐永灿.酒石酸锗复合物的镇痛作用[J].延边医学院学报,1994,17(2):112-114. |
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| 作者姓名： | 金正男 徐永灿 |
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| 作者单位： | 延边医学院药理学教研室，延边医学院化工制药机械教研室，延边医学院有机锗研究所 |
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| 摘 要： | 探讨了酒石酸锗复合物的镇痛作用．灌胃酒石酸锗夏合物２０，４０，２００ｍｇ·ｋｇ－１，在热板法镇痛实验时明显地提高痛阈（Ｐ＜０．０５，Ｐ＜０．０１或Ｐ＜０．００１），非常明显地延长扭体反应出现时间（Ｐ＜０．００１），减少扭体反应次数（Ｐ＜０．００１）．结果提示，酒石酸锗复合物具有良好的镇痛作用．
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| 关 键 词： | 止痛 酒石酸盐类 锗 小鼠 |
Experimental study on analgesic effects of germanium tartrate com-plex in mice |
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| Jin
Zhengnan,Xu Yongcan,Luo Yongshan,Piao Shihao,Jin Jingji.Experimental study on analgesic effects of germanium tartrate com-plex in mice[J].Journal of Medical Science Yanbian University,1994,17(2):112-114. |
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| Authors: | Jin
Zhengnan Xu Yongcan Luo Yongshan Piao Shihao Jin Jingji |
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| Institution: | Jin
Zhengnan1,Xu Yongcan2,Luo Yongshan3,Piao Shihao1,Jin Jingji11Department of
Pharmacology,Yanbian medical College2Pharmaceutical Mechanical Department of Chemical
Industy,Yanbian Medical College3Institute of Organogermanium,Yanbian MedicaI Colle |
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| Abstract: | The analgesic action of germanium tartrate complex was studied. The germanium
tar-trate complex(20, 40, 200 mg/kg, ig.) significantly increased the pain threshold in hotplate
reaction(P<0.05,P<0.0l or P<0.001 ), delayed the potential period of writhing(P<0.001 ),and
decreased the numher of writhing(P<0.001 ) in mice. These results sug-gest that germanium
tartrate complex has a good effect on analgesia. |
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| Keywords: | analgesia tartrates germanium mice |
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