大鼠脊髓向延髓网状背侧亚核投射神经元的形态及分布

既往的电生理学研究已经证实,位于延髓尾侧部的网状背侧亚核（subnucleusretlcularlsdorsalls．SRD）对伤害性信息的调控具有重要作用j',SRD神经元可被来自全身各部的AS或C纤维的冲动所兴奋,这种兴奋可被吗啡抑制,又可被纳洛酮所翻转"。。形态学研究也表明,在脊髓和S...

MORPHOLOGY AND DISTRIBUTION OF THE NEURONS PROJECTING FROM SPINAL CORD TO THE SUBNUCLEUS RETICULARIS DORSALIS OF THE RAT

In order to study the morphology and distribution of the projecting neurons from the spinal cord to the subnucleusreticularis dorsalis (SRD) in medulla and the relationship between the projecting neurons and SP,the fluorogold(FG)and SP receptor immunohistochemical double-labeling method were used following electrophoretic injection of FG into SRD of the rat. Theresults showed that the neurons labeled retrogradely with FG were mainly localized in ipsilateral laminae Ⅲ.～ and, especially in laminae and , a few labeling neurons were detected on contralateral side. In lamina , the percentage of neuronsdouble labeled with FG and SP receptor was about 35% of FG immunoreactive neurons. In laminae ～, the percentage ofdouble labeled neurons was about 20%. The results suggested thai SP released from primary afferent fibers could directly act onthe SRD projecting neurons of the above mentioned laminae.