我国部分地区成年人血浆叶酸的地区和季节差异比较

目的：描述我国部分地区成年人群血浆叶酸在不同地区、季节的分布特征。方法：以来自南北方有代表性的城乡地区2 545人（35-64岁）为研究样本,对其血浆叶酸分布特点进行统计学分析。结果：南方人群血浆叶酸平均水平（16.9nmol/L）显著高于北方人群（8.3nmol/L）,北方人群叶酸缺乏率（37.0%）显著高于南方人群（5.8%）;南北方人群血浆叶酸水平随季节变化规律不同,南方人群夏秋季血浆叶酸水平（15.0nmol/L）低于冬春季节（18.8nmol/L）,叶酸缺乏率变化不明显;北方人群夏秋季节血浆叶酸水平（9.7nmol/L）明显高于冬春季节（7.1nmol/L）,叶酸缺乏率夏秋季节为26.2%,显著低于冬春季节的48.0%。结论：我国南北地区成年人群血浆叶酸水平差异显著;南北方人群血浆叶酸随季节变化规律不同。

Variation of plasma folate levels in adults between some areas and different seasons in China

Objective To describe the distribution of plasma folate concentrations and prevalence of folate deficiency in adults aged 35 to 64 years in some areas and different seasons in China Methods Study subjects were sampled from the representative rural and urban areas in the south and north of China aged 35 to 64 years totaling 2 545, and their plasma folate concentrations were determined and analyzed Results Plasma concentrations of folate in the southern population were significantly higher (16.9 nmol/L) than those in the north (8.3 nmol/L), and the prevalence of folate deficiency in the south (5.8%) was significantly lower than that in the north (37.1%). Plasma folate concentration varied with season either in the south or north. Plasma concentrations of folate were lower during the summer and the fall(15.0 nmol/L)than those during the winter and the spring(18.8 nmol/L)in the south, but without significant changes in the prevalence of folate deficiency in different seasons. However, the plasma folate concentrations were significantly higher during the summer and the fall(9.7 nmol/L)than those during the winter and the spring (7.1 nmol/L) in the north.And the prevalence of folate deficiency in the north was significantly higher in winter and spring (48.0%) than that in summer and fall (26.2%) Conclusions There existed significant difference in plasma folate concentrations in adults between varied geographic areas in China, which differed from their seasonal changes.