Prospective randomized trial of paravertebral block for patients undergoing breast cancer surgery |
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| Authors: | Judy C. Boughey Farzin Goravanchi Ronald N. Parris Spencer S. Kee Alicia M. Kowalski John C. Frenzel Isabelle Bedrosian Funda Meric-Bernstam Kelly K. Hunt Frederick C. Ames Henry M. Kuerer Anthony Lucci |
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| Affiliation: | a Department of Surgery, The University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA
b Department of Anesthesia, The University of Texas, M.D. Anderson Cancer Center, Houston, TX, USA |
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| Abstract: | BackgroundThe goal of the current study was to evaluate the effect of regional anesthesia using paravertebral block (PVB) on postoperative pain after breast surgery.MethodsPatients undergoing unilateral breast surgery without reconstruction were randomized to general anesthesia (GA) only or PVB with GA and pain scores assessed.ResultsEighty patients were randomized (41 to GA and 39 to PVB with GA). Operative times were not significantly different between groups. Pain scores were lower after PVB compared to GA at 1 hour (1 vs 3, P = .006) and 3 hours (0 vs 2, P = .001) but not at later time points. The overall worst pain experienced was lower with PVB (3 vs 5, P = .02). More patients were pain-free in the PVB group at 1 hour (44% vs 17%, P = .014) and 3 hours (54% vs 17%, P = .005) postoperatively.ConclusionsPVB significantly decreases postoperative pain up to 3 hours after breast cancer surgery. |
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| Keywords: | Breast surgery Paravertebral block Regional anesthesia Postoperative pain Pain control Length of stay |
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