已婚妇女人乳头瘤病毒感染流行病学调查

目的探讨已婚妇女人乳头瘤病毒（HPV）感染现况及影响因素。方法随机抽取三个社区1155名已婚女性进行问卷调查、妇科检查和HPVDNA检测。结果HPV感染率为12．99％，其中HR-HPV感染率为11．77％，显著高于LR-HPV感染。单一感染率显著高于复合感染（P〈0．01）。不同年龄段及宫颈糜烂程度的HR-HPV感染率差异有统计学意义（P〈0．05），性生活频率、使用避孕套及吸烟史与HR-HPV感染相关（P〈0．05）。宫颈糜烂、性生活频率是HR-HPV感染危险因素，使用避孕套对HR-HPV感染有保护作用（P〈0．05）。结论海宁市社区育龄期、围绝经期妇女HPV及HR-HPV感染率较高．与性接触及宫颈炎症有关，使用避孕套可降低HPV的感染率。

Epidemiological survey and risk factors of human papillomavirus infection status in married women

Objective To investigate human papillomavirus(HPV) infection status and influencing factors of married women.Methods RandomLy selected 1155 married women in 3 communities conducted a questionnaire survey,gynecological examination and HPV DNA testing.Results HPV infection rate was 12.99%,of which HR-HPV infection rate of 1 1.77% was significantly higher than LR-HPV infection,the infection rate was significantly higher than a single composite infection(P < 0.01).Different ages and degrees of cervical erosion,HR-HPV infection was significantly(P < 0.05).Sexual frequency,condom use and smoking were related to HR-HPV infection(P < 0.05).Cervical erosion,sexual frequency were the risk factors for HR-HPV infection,condoms use was protection factors for HR-HPV infection(P < 0.05).Conclusion HR-HPV infection of reproductive age,perimenopausal women in Haining city community is high,and is related to sexual contact and cervical inflammation,condoms use could reduce the HVP infection rates.