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静注免疫球蛋白联合更昔洛韦治疗病毒性脑膜炎的临床分析
引用本文:白银雪. 静注免疫球蛋白联合更昔洛韦治疗病毒性脑膜炎的临床分析[J]. 航空航天医学杂志, 2021, 32(1): 8-9
作者姓名:白银雪
作者单位:南阳医学高等专科学校第一附属医院神经内科,河南南阳473000
摘    要:目的 探讨静注免疫球蛋白联合更昔洛韦治疗病毒性脑膜炎的临床效果.方法 选取2017年7月-2018年7月治疗的病毒性脑膜炎患者90例,按照随机抽签法分组,对照组45例,单独使用更昔洛韦治疗,观察组45例,用静注免疫球蛋白联合更昔洛韦治疗.对比两组治疗后白细胞因子水平及临床疗效.结果 治疗前,两组白细胞介素-1、肿瘤坏死...

关 键 词:病毒性脑膜炎  静注免疫球蛋白  更昔洛韦  白细胞介素-1、肿瘤坏死因子-α

Clinical Analysis of Intravenous Immunoglobulin Combined with Ganciclovir in the Treatment of Viral Meningitis
BAI Yinxue. Clinical Analysis of Intravenous Immunoglobulin Combined with Ganciclovir in the Treatment of Viral Meningitis[J]. Journal of Aerospace medicine, 2021, 32(1): 8-9
Authors:BAI Yinxue
Affiliation:(Department of Neurology,the First Affiliated Hospital of Nanyang Medical College,Nanyang,Henan 473000,China)
Abstract:Objective To explore the clinical effect of intravenous immunoglobulin combined with ganciclovir in the treatment of viral meningitis. Methods 90 patients with viral meningitis treated in our hospital from July 2017 to July 2018 were selected and grouped according to the random drawing method. The control group was 45 cases and was treated with ganciclovir alone. The observation group was 45 cases. Intravenous immunoglobulin combined with ganciclovir treatment. Compare the level of leukocyte factor and clinical efficacy of the two groups after treatment. Results Before treatment, there was no significant difference in the levels of interleukin-1 and tumor necrosis factor-α between the two groups(P>0.05). After treatment, the levels of interleukin-1 and tumor necrosis factor-α in the observation group were lower than those in the control group(P<0.05). The effective rate of clinical treatment in the observation group was 97.8%, and the effective rate of clinical treatment in the control group was 80.0%. The difference between the two groups was significant(P<0.05). Conclusions Intravenous immunoglobulin combined with ganciclovir in the treatment of viral meningitis can improve the levels of interleukin-1 and tumor necrosis factor-α factor in patients. The clinical effect is good and can be promoted.
Keywords:viral meningitis  intravenous immunoglobulin  ganciclovir  interleukin-1  tumor bad Death factor-α
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