超声影像组学标签预测三阴性乳腺癌的价值

目的 探讨基于常规超声的影像组学标签在术前诊断三阴性乳腺癌(TNBC)的价值.资料与方法 回顾性连续收集230例经手术病理证实的肿块型浸润性乳腺癌患者的临床资料和术前超声图像,按照1:2随机抽样选取TNBC与非TNBC共102例患者纳入本研究.按超声检查时间顺序,将患者分为训练组66例和验证组36例.通过ImageJ软...

Ultrasound-Based Radiomics in Predicting Triple-Negative Breast Cancer

Purpose To explore the value of a radiomics model based on ultrasound imaging in predicting triple-negative breast cancer(TNBC)before surgery.Materials and Methods A total of 230 patients with invasive breast cancer were retrospectively analyzed,all patients underwent breast ultrasound examination before surgery.A total of 102 patients were randomly selected according to the ratio of 1∶2(TNBC vs.non-TNBC).According to the order of examination time,all patients were divided into 66 cases of training group and 36 cases of validation group.ImageJ software was used to manually delineate the lesion area in the ultrasound image along the tumor boundary.Pyradiomics was used to extract 1820 features from each lesion area,and Logistic regression model was used to construct ultrasound imaging radiomics model.The receiver operating characteristic(ROC)curve was used to evaluate the value of ultrasound imaging radiomics model in predicting TNBC.Results Finally,4 key image features were selected to construct ultrasound imaging radiomics model.The area of under the ROC curve of the model in the training group and the validation group were 0.866(95%CI 0.768-0.964)and 0.844(95%CI 0.716-0.972),respectively.The calibration curve showed that the model had a good calibration in both the training and validation groups;besides,the decision curve analysis confirmed that the model could support clinical decision-making.Conclusion Ultrasound-based imaging radiomics model is of great value in predicting TNBC before surgery.