Correlation of Patient-reported Symptom Outcomes and Treadmill Test Outcomes after Treatment for Aortoiliac Claudication |
| |
| Authors: | Timothy P. Murphy Matthew R. Reynolds David J. Cohen Judith G. Regensteiner Joseph M. Massaro Donald E. Cutlip Emile R. Mohler Joselyn Cerezo Niki C. Oldenburg Claudia C. Thum Suzanne Goldberg Alan T. Hirsch |
| |
| Affiliation: | 1. Department of Diagnostic Imaging, Vascular Disease Research Center, Rhode Island Hospital, Gerry 337, 593 Eddy Street, Providence, RI 02903;2. Department of Internal Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts;3. Harvard Clinical Research Institute, Boston, Massachusetts;4. Department of Biostatistics, Boston University, Boston, Massachusetts;5. Department of Internal Medicine, University of Missouri-Kansas City, Kansas City, Missouri;6. Department of Exercise Physiology, University of Colorado School of Medicine, Aurora, Colorado;7. Department of Internal Medicine, University of Pennsylvania, Philadelphia, Pennsylvania;8. Department of Epidemiology, University of Minnesota Medical School, Minneapolis, Minnesota;9. Department of Internal Medicine, University of Minnesota Medical School, Minneapolis, Minnesota;10. National Heart, Lung and Blood Institute, Bethesda, Maryland |
| |
| Abstract: | PurposeTo examine the relationship between objective treadmill test outcomes and subjective symptom outcomes among patients with claudication treated with stent revascularization (ST) compared with supervised exercise (SE).Materials and MethodsFive scales of the Peripheral Artery Questionnaire and Walking Impairment Questionnaire were correlated with peak walking time and treadmill claudication onset time.ResultsThe correlation between change in disease-specific quality of life (QOL) and change in peak walking time differed according to treatment group, with statistically significant correlations for all five scales for the ST group and weaker trends for the SE group, only one of which was statistically significant. In contrast, improvements in disease-specific QOL correlated well with increases in claudication onset time, with no significant interaction with treatment group for any of the five scales.ConclusionsDisease-specific QOL results at 6 months in the Claudication: Exercise Vs. Endoluminal Revascularization (CLEVER) study show that improved maximal treadmill walking in patients with claudication treated with SE correlated poorly with self-reported symptom relief. Conversely, patients treated with ST showed good correlation between improved maximal treadmill walking and self-reported symptom improvement. The correlation between claudication onset time and self-reported symptom relief was good across treatment groups. This finding indicates that traditional objective treadmill test outcomes may not correlate well with symptom relief in patients with claudication. Future studies should investigate these data and improve understanding of patient relevance of traditional objective treadmill-based treatment outcomes. |
| |
| Keywords: | CLEVER" },{" #name" :" keyword" ," $" :{" id" :" key0010" }," $$" :[{" #name" :" text" ," _" :" Claudication: Exercise Vs. Endoluminal Revascularization COT" },{" #name" :" keyword" ," $" :{" id" :" key0020" }," $$" :[{" #name" :" text" ," _" :" claudication onset time OMC" },{" #name" :" keyword" ," $" :{" id" :" key0030" }," $$" :[{" #name" :" text" ," _" :" optimal medical care PAD" },{" #name" :" keyword" ," $" :{" id" :" key0040" }," $$" :[{" #name" :" text" ," _" :" peripheral artery disease PAQ" },{" #name" :" keyword" ," $" :{" id" :" key0050" }," $$" :[{" #name" :" text" ," _" :" Peripheral Artery Questionnaire PWT" },{" #name" :" keyword" ," $" :{" id" :" key0060" }," $$" :[{" #name" :" text" ," _" :" peak walking time QOL" },{" #name" :" keyword" ," $" :{" id" :" key0070" }," $$" :[{" #name" :" text" ," _" :" quality of life SE" },{" #name" :" keyword" ," $" :{" id" :" key0080" }," $$" :[{" #name" :" text" ," _" :" supervised exercise ST" },{" #name" :" keyword" ," $" :{" id" :" key0090" }," $$" :[{" #name" :" text" ," _" :" stent revascularization WIQ" },{" #name" :" keyword" ," $" :{" id" :" key0100" }," $$" :[{" #name" :" text" ," _" :" Walking Impairment Questionnaire |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
