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Impact of mechanical stress and tension-stress on angiogenesis in wound healing
作者姓名:王海强  赵黎
作者单位:PLA Institute of Orthopaedics Xijing Hospital Fourth Military Medical University,Xi'an 710032,China,PLA Institute of Orthopaedics Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China
摘    要:Angiogenesis plays a fundamental role in the development of the embryonic vascular tree as well as in several normal and pathologic conditions during postnatal life. Blood supply, established by neovascularization. is imperative for histogenesis during wound healing as well as the limb lengthening applied extensively in the treatment of skeletal trauma sequalae. But little attention has been paid to this area. This review aims to summarize angiogenesis regulation, the process of angiogenesis in wound healing and angiogenesis under mechanical stress, particularly in association with the tension-stress principle.

关 键 词:机械压力  冲击伤  伤口愈合  血管生成
收稿时间:2005-05-26

Impact of mechanical stress and tension-stress on angiogenesis in wound healing
WANG Hai-qiang,ZHAO Li.Impact of mechanical stress and tension-stress on angiogenesis in wound healing[J].Chinese Journal of Traumatology(English Edition),2006,9(2):118-124.
Authors:WANG Hai-qiang  ZHAO Li
Institution:PLA Institute of Orthopaedics, Xijing Hospital, Fourth Military Medical University, Xi'an 710032, China
Abstract:Angiogenesis plays a fundamental role in the development of the embryonic vascular tree as well as in several normal and pathologic conditions during postnatal life. Blood supply, established by neovascularization. is imperative for histogenesis during wound healing as well as the limb lengthening applied extensively in the treatment of skeletal trauma sequalae. But little attention has been paid to this area. This review aims to summarize angiogenesis regulation, the process of angiogenesis in wound healing and angiogenesis under mechanical stress, particularly in association with the tension-stress principle.
Keywords:Wound healing  Stress  mechanical  Angiogenesis
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