Relationship between oxygen anion-radical generation and lipid peroxidation in liver microsomes |
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| Authors: | V. M. Mishin A. G. Pokrovskii L. N. Pospelova V. V. Lyakhovich |
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| Abstract: | Determination of the O2 consumption and accumulation of malondialdehyde, induced by phenobarbital and 3-methylcholanthrene in rat or rabbit liver microsomes revealed inhibition of lipid peroxidation but a relatively high level of O2 ?-radical generation. It is postulated that the absence of direct correlation between lipid peroxidation activity and O2 ? generation in microsomes depends on the antioxidant level in the microsomal membrane. |
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