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联合检测CA125、CA19-9作为卵巢上皮癌诊断及疗效观察指标的研究
引用本文:马道新,刘春生,秦雪梅,王文霞.联合检测CA125、CA19-9作为卵巢上皮癌诊断及疗效观察指标的研究[J].山东大学学报(医学版),2001,39(5):462-463.
作者姓名:马道新  刘春生  秦雪梅  王文霞
作者单位:山东大学齐鲁医院肿瘤中心血液病研究室
摘    要:目的探讨CA125、CA19-9联合检测在卵巢上皮癌诊断及疗效观察中的意义.方法利用ELISA方法对卵巢上皮癌、子宫内膜异位症和乳腺癌与正常对照组同时进行CA125、CA19-9的检测.结果卵巢癌CA125诊断灵敏度高,术前水平明显高于术后和其它各组.CA125与CA19-9联合检测使卵巢癌检出率明显提高.结论CA125是卵巢上皮癌诊断及判断预后的特异性指标,CA125和CA19-9联合应用可明显提高卵巢上皮癌检出率.

关 键 词:卵巢肿瘤  抗原  肿瘤相关  碳水化合物
文章编号:1000-0496(2001)05-0462-02
修稿时间:1998年12月10

STUDY ON COMBINATION OF CA19-9 AND CA125 IN DIAGNOSIS AND PROGNOSIS OF OVARIAN CANCER
MA Dao-xin,LIU Chun-sheng,QIN Xue-mei,et al.STUDY ON COMBINATION OF CA19-9 AND CA125 IN DIAGNOSIS AND PROGNOSIS OF OVARIAN CANCER[J].Journal of Shandong University:Health Sciences,2001,39(5):462-463.
Authors:MA Dao-xin  LIU Chun-sheng  QIN Xue-mei  
Abstract:Objective:To explore the value of combining CA19-9 and CA125 in diagnosis and prognosis of ovarian cancer.Methods:ELISA method was used to detect CA19-9 and CA125 of ovarian cancer,endometiosis,breast cancer patients and controls.Results:The CA125 positive rate and level before surgery were higher than those of other groups.The positive rate of ovarian cancer when combining CA125 and CA19-9 was higher than that of single CA125.Conclusion:CA125 is the specific index in diagnosis and prognosis of ovarian cancer,and it will be better to diagnose ovarian cancer when combining CA125 and CA19-9 together.
Keywords:Ovarian neoplasms  Antigens  tumor-associated  Carbohydrates
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