Experimental comparison between the effect of standardized trazodone-amitriptyline and placebo treatment in vitalized depressive patients |
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Authors: | E. Klieser E. Lehmann |
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Affiliation: | (1) Psychiatry Division, University of Düsseldorf-Rheinische Landesklinik, D-4000 Düsseldorf, Federal Republic of Germany |
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Abstract: | We are performing a double-blind trial with inward psychiatric patients. The indication for our psychotropic or psychotherapeutic intervention is mainly severe depression (=major depressive disorders DSM III). For a 3-week trial course trazodone (400 mg daily), amitriptyline (150 mg/die) or placebo capsules were given at random. All patients received the same type of cognitive behaviour therapy. The test battery consists of CGI, BPRS, HAMD, HAMA and AMDP; adverse drug reactions are documented as free reports (=freier Nebenwirkungsbericht). The interim results (until March 1987) will be presented. Our investigation indicates that it is probable that the trazodone treatment we used is equivalent to corresponding amitriptyline treatment. |
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Keywords: | Trazodone Amitriptyline Placebo treatment |
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