| 骨复生对激素性股骨头缺血坏死家兔氧自由基的影响 |
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| 引用本文： | 王国毓,姚永东,杨毓华,李堪印,朱长庚,李彦民,刘德玉.骨复生对激素性股骨头缺血坏死家兔氧自由基的影响[J].中医正骨,2002,14(1):8-8. |
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| 作者姓名： | 王国毓 姚永东 杨毓华 李堪印 朱长庚 李彦民 刘德玉 |
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| 作者单位： | 陕西中医学院附属医院,咸阳,712083 |
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| 摘 要： | 采用给日本大耳白兔大剂量肌注醋酸氢化考的松 8mg·kg-1,造成激素性股骨头缺血坏死的病理模型 ,通过设立骨复生组、模型组、空白组 ,观察血液中红细胞SOD活力及血浆LPO含量的变化 ,发现骨复生具有升高红细胞SOD活力、降低血浆LPO含量的作用。而这些作用是其治疗激素性股骨头缺血坏死的可能机制之一。
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| 关 键 词： | 股骨头坏死/中医药疗法 骨复生/治疗应用 氧自由基/血液 SOD活力/血液 LPO/血液 实验研究 动物 兔 |
| 文章编号： | 1001-6015(2002)01-0008-01 |
| 修稿时间： | 2000年11月27 |
THE INFLUENCE OF GUFUSHENG ON OXYGEN FREE RADICAL IN RABBITS WITH STEROID-INDUCED AVASCULAR NECROSIS OF FEMORAL HEAD: An Experimental Study |
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| Wang Guoyu,Yao Yongdong,Yang Yuhua,et al Hospital Affiliated to Shanxi College of TCM,Xianyang.THE INFLUENCE OF GUFUSHENG ON OXYGEN FREE RADICAL IN RABBITS WITH STEROID-INDUCED AVASCULAR NECROSIS OF FEMORAL HEAD: An Experimental Study[J].The Journal of Traditional Chinese Orthopedics and Traumatology,2002,14(1):8-8. |
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| Authors: | Wang Guoyu Yao Yongdong Yang Yuhua Hospital Affiliated to Shanxi College of TCM Xianyang |
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| Institution: | Wang Guoyu,Yao Yongdong,Yang Yuhua,et al Hospital Affiliated to Shanxi College of TCM,Xianyang 712083 |
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| Abstract: | To study the influence of Gufusheng on oxygen free radical in rabbits with steroid induced avascular necrosis of femoral head, 30 Japanese white rabbits with big ears were divided into 3 groups randomly: Gufusheng group and two control group ( model group, blank group). Except for the blank group, the others were made pathological models by injecting hydrocortisone acetate twice every week. After completing the modeling process, the activity of SOD in red blood and the content of LPO in plasma were measured. The results showed that Gufusheng could lower the content of LPO in plasma, and enhance the activity of red blood, which might be the mechanism of curing steroid induced avascular necrosis of femoral head with Gufusheng. |
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| Keywords: | steroid induced avascular necrosis of femoral head /TCM therapy Gufusheng/therapeutic application oxygen free radical the activity of SOD/ blood LPO/blood experimental study animal rabbit |
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