| 表皮生长因子影响肿瘤病人舌苔形成的机理探讨 |
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| 引用本文： | 许冬青,王明艳,梁枫,詹臻.表皮生长因子影响肿瘤病人舌苔形成的机理探讨[J].口腔医学研究,2007,23(6):604-606. |
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| 作者姓名： | 许冬青 王明艳 梁枫 詹臻 |
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| 作者单位： | 1. 南京中医药大学基础医学院,江苏,南京,210029
2. 安徽中医药高等专科学校医疗系 |
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| 基金项目： | 国家自然科学基金(编号:30472123,30070910) |
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| 摘 要： | 目的:研究表皮生长因子(EGF)对舌鳞癌细胞Tca-8113株粘附分子CD29、CD54、CD106表达的影响,探讨EGF促进肿瘤患者舌苔增厚的分子机制。方法:应用流式细胞术,检测CD29、CD54、CD106的表达。结果:EGF能明显促进Tca-8113细胞膜上CD29、CD54的表达,但对CD106的表达影响不明显。结论:EGF可能通过促进CD29、CD54的表达影响舌苔形成。
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| 关 键 词： | EGF 舌苔 Tca-8113 CD29 CD54 CD106 |
| 文章编号： | 1671-7651（2007）06-0604-03 |
| 收稿时间： | 2007-10-22 |
| 修稿时间： | 2007年10月22 |
Molecular Mechanism of the Effects of EGF on Tongue Fur Formation of Tumor Patients |
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| XU Dong - qing, WANG Ming -yan, LIANG Feng,et al..Molecular Mechanism of the Effects of EGF on Tongue Fur Formation of Tumor Patients[J].Journal of Oral Science Research,2007,23(6):604-606. |
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| Authors: | XU Dong - qing WANG Ming -yan LIANG Feng |
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| Institution: | XU Dong - qing, WANG Ming -yan, LIANG Feng, et al. |
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| Abstract: | Objective:To investigate the effects of epidermal growth factor(EGF)on the expressions of CD29,CD54,CD106 on Tca-8113 and explore molecular mechanism of tongue fur formation of tumor patients by EGF.Methods:The expressions of CD29,CD54,CD106 of Tca-8113 were detected by flow cytometry(FCM).Results:EGF could significantly up regulate expressions of CD29,CD54,but could not significantly regulate the expression of CD106.Conclusion:EGF may affect the formation of tongue fur by up regulating the expressions of CD29 and CD54. |
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| Keywords: | EGF CD29 CD54 CD106 FCM Fur of tongue |
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