持续性心房颤动患者使用华法林抗凝治疗稳定性影响因素的临床研究

目的:探索影响心房颤动(房颤)患者在使用华法林抗凝治疗过程中稳定性达标的因素,以期为改善华法林的抗凝质量提供参考.方法:选取2019年1月-2019年12月就诊于南昌大学附属九江医院(九江市第一人民医院)的337例使用华法林抗凝治疗的持续性房颤患者,计算分析华法林真实抗凝世界的稳定性达标率等参数,并分析包括年龄、性别、...

Clinical study on influencing factors to stability of warfarin anticoagulant therapy in patients with persistent atrial fibrillation

Objective: To explore the factors affecting the stability of patients with atrial fibrillation during warfarin anticoagulant therapy, in order to provide reference for improving the anticoagulant quality of warfarin. Methods: The 337 patients with persistent atrial fibrillation treated with warfarin were selected in Jiujiang Hospital Affiliated to Nanchang University(Jiujiang first people’s Hospital) from January 2019 to December 2019. The stability compliance rate of warfarin in the real anticoagulant world was calculated and analyzed. Some factors including age, gender, combined diseases, smoking, drinking, drinking green tea and increased platelet distribution width were studied in study of stability of warfarin anticoagulant therapy. Results: The compliance rate of anticoagulant stability of warfarin was 18.69%. The relevant factors affecting the compliance rate of anticoagulant stability of warfarin included age, drinking alcohol, drinking green tea, with the increase of platelet distribution width. Patients with atrial fibrillation with increased platelet distribution width had a lower compliance rate of anticoagulant stability of warfarin during follow-up. Conclusion: The stability compliance rate of warfarin anticoagulant therapy is low. Age, drinking, drinking green tea and the increase of platelet distribution width will affect the stability of warfarin anticoagulant therapy.